RecruitingNot ApplicableNCT06576908

Evaluation of On-Couch CBCT Image Quality

Evaluation of Image Quality From an On-Couch, Cone Beam Computed Tomography (CBCT) Radiation Treatment System for Image Guidance and Treatment Adaptation


Sponsor

Varian, a Siemens Healthineers Company

Enrollment

46 participants

Start Date

Oct 17, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This is a prospective, single-arm, single-site study designed to generate data describing the image quality and applicability/useability of a high-performance, on-couch CBCT imaging technology (HyperSight) in patients receiving radiation treatment for cancer on a C-arm linear accelerator (TrueBeam).


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Patient age is ≥ 18 years old.
  • Patient has a diagnosis of primary or metastatic cancer, including but not limited to tumors arising from or involving the head/neck, lungs, liver, pancreas, prostate, urinary bladder, rectum, cervix or uterus.
  • A previous (standard-of-care) decision was made to treat the patient with radiation therapy using a Varian TrueBeam treatment system.
  • A previous (standard-of-care) decision was made to treat the patient with a radiation dose of at least 20 Gy in at least 5 fractions, one fraction per day on consecutive days, Monday to Friday.
  • Patient is willing and able to provide informed consent to participate in the study.

Exclusion Criteria2

  • Patient is pregnant or has plans for pregnancy during the period of treatment.
  • Patient is part of a vulnerable population (per ISO 14155:2020, "individuals who are unable to fully understand all aspects of the investigation that are relevant to the decision to participate, or who could be manipulated or unduly influenced as a result of a compromised position, expectation of benefits or fear of retaliatory response").

Interventions

DEVICEHyperSight Imaging

Subjects receive both HyperSight imaging and conventional imaging, on their first day of radiation treatment, on their second day of treatment, and on their last day of treatment.


Locations(1)

Princess Margaret Cancer Centre (University Health Network)

Toronto, Ontario, Canada

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NCT06576908


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