RecruitingNCT06580158

AI in Outpatient Practice for Diagnosing Aortic Stenosis and Diastolic Dysfunction

The Clinical Utility of Artificial Intelligence-enabled Electrocardiograms in the Outpatient Practice - Diagnosing Aortic Stenosis and Diastolic Dysfunction


Sponsor

Mayo Clinic

Enrollment

2,000 participants

Start Date

Nov 8, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Two recently developed artificial intelligence-enabled electrocardiogram (AI-ECG) models have been developed to detect aortic stenosis (AS) and diastolic dysfunction (DD). AI-ECG for AS has a sensitivity of 78% and specificity of 74%, and AI-ECG for DD has a sensitivity of 83% and specificity of 80%. However, these models have never been prospectively applied to diagnose AS or DD, which may be useful for patients and providers from a diagnostic and prognostic perspective and especially in settings where access to higher- level medical care is limited. In this study, we aim to determine the clinical utility of these AI-ECG models by prospectively applying them to an outpatient cohort and then completing a focused point-of-care ultrasound to evaluate those who are AI-ECG positive for AS and DD.


Eligibility

Min Age: 60 Years

Inclusion Criteria1

  • ≥ 60 years of age must have a clinical scheduled ECG performed.

Exclusion Criteria3

  • \< 59 years of age
  • Is not scheduled for a clinical ECG
  • Unable to provide consent.

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Interventions

DEVICEAI-ECG Dashboard

Patients standard of care ECG's will be processed through the AI-ECG Dashboard

DIAGNOSTIC_TESTPoint of care ultrasound (POCUS)

Patients will undergo a ultrasound to confirm diagnosis of atrial stenosis or diastolic dysfunction.


Locations(1)

Mayo Clinic

Rochester, Minnesota, United States

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NCT06580158


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