RecruitingNCT06580639

The Role of a Mycobacterium Growth Inhibition Assay to Quantify Host Immune Control of M. Tuberculosis

The Role of a Mycobacterium Growth Inhibition Assay to Quantify Host Immune Control of M. Tuberculosis From Healthy Blood Donors and Patients With Latent or Active Tuberculosis.


Sponsor

Linkoeping University

Enrollment

280 participants

Start Date

Aug 1, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to learn about how the blood leucocytes from patients with and without exposure or disease from tuberculosis (TB) are able to kill live mycobacteria (M. tuberculosis). The main question it aims to answer is: Is intracellular growth suppression of M. tuberculosis in peripheral blood mononuclear cells variable among healthy blood donors and higher than in patients with latent TB compared to active TB?


Eligibility

Min Age: 18 Years

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Interventions

OTHERNo intervention.

Blood sampling for analysis of mycobacterial growth inhibition assay (MGIA) analysis.


Locations(2)

Kalmar County Hospital

Kalmar, Sweden

Dept of Infectious Diseases

Linköping, Sweden

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NCT06580639


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