RecruitingNot ApplicableNCT06585631

The Collaborative Care PrTNER Study

The Collaborative Care PrTNER (Prevention, Treatment, Navigation, Engagement, Resource) Project

Sponsor

Children's Hospital of Philadelphia

Enrollment

275 participants

Start Date

Jan 2, 2025

Study Type

INTERVENTIONAL

Conditions

Substance Use Disorders HIV Substance Use AIDS

Summary

A randomized controlled trial to assess the ability of a Collaborative Care Prevention, Treatment, Navigation, Engagement, Resource (PrTNER) intervention to increase initiation of preexposure prophylaxis (PrEP) (for those at-risk for HIV) and decrease viral load (for those living with HIV) among young Black and Latino men who have sex with men (YBLMSM) aged 15 to 24 through engagement in SU treatment.

Eligibility

Sex: MALEMin Age: 15 YearsMax Age: 24 Years

Inclusion Criteria20

Aim 1:
years old;
Cisgender male;
Self-identified Black/African American race or Latino/Hispanic ethnicity;
Report prior oral/anal sex with another male;
At-risk for HIV (condomless anal sex or positive sexually transmitted infection (STI) in last 6 months);
Moderate-to-high risk SU behaviors based upon a Car, Relax, Alone, Forget, Friends, Trouble (CRAFFT) score ≥2,
Living in Philadelphia, PA or Baltimore, MD, and surrounding areas;
Able to read and write in English
Aim 2:
years old;
Cisgender male;
Self-identified Black/African American race or Latino/Hispanic ethnicity;
Report prior oral/anal sex with another male;
Living with a diagnosis of HIV;
CRAFFT score ≥2,
Living in Philadelphia, PA or Baltimore, MD, and surrounding areas;
Able to read and write in English
Aim 3
• All randomized study participants will be included in Aim 3.

Exclusion Criteria12

Aim 2:
Participants will be excluded if they are:
Assigned female sex at birth
Identify as transgender
Outside the age criteria (\<15 or \>24 years old)
Cognitively unable to complete study requirements
Living outside of the two geographic areas
Do not screen positive for SU
No prior substance use history
No prior oral or anal sex;
Unable to read or write in English,
Plan to move in the next 12 months.

Interventions

BEHAVIORALCC PrTNER

Participants randomized to CC PrTNER will be assigned a peer coach. They will conduct interviewer-administered behavioral surveys. The surveys provide an in-depth assessment of SU, HIV prevention and care, engagement, and adherence. Behavioral surveys are administered monthly. The coach will discuss with the participant the areas that are flagged by the psychiatrist; provide psychoeducation around areas identified, and work with the participant to identify their health goals and how changes in SU may help feed into self-defined goals. The coach will meet weekly with the consultant addiction psychiatrist who will make a provisional diagnosis and define a treatment plan with clear goals for treatment outcome. Recommendations will be communicated electronically to the HIV or PrEP provider to facilitate implementation. The coach utilizes MI skills to implement the individually tailored to facilitate the adoption and maintenance of health behaviors.