Testicular Function and Semen Quality in Male Childhood and Adolescent Cancer Survivors

This study is investigating how cancer treatment during childhood or adolescence affects fertility and testicular function in male survivors who are now adults. Researchers will analyze sperm quality and hormone levels to understand the long-term reproductive effects of pediatric cancer therapy. **You may be eligible if...** - You are a male between 18 and 50 years old - You were treated with chemotherapy and/or radiation for cancer diagnosed before age 18 - Your cancer has been in remission for at least 2 years - You are able to provide a semen sample by masturbation **You may NOT be eligible if...** - You are unable to provide a semen sample - You have a history of undescended testes (cryptorchidism) or testicular cancer - You have had a vasectomy - You are currently on testosterone replacement therapy - You are unwilling to participate Talk to your doctor to see if this trial is right for you.