Testicular Function and Semen Quality in Male Childhood and Adolescent Cancer Survivors
Effect of Cancer Treatment on Testicular Function and Semen Quality in Male Childhood and Adolescent Cancer Survivors
The University of Hong Kong
200 participants
Jan 16, 2023
OBSERVATIONAL
Conditions
Summary
Cancer treatment can affect the testicular function, including sperm and hormonal functions. The aim of this study is to assess the testicular function and semen quality in young men who recover from childhood and adolescent cancer in Hong Kong. This can provide more information for pre-treatment counselling as well as improve post treatment survivorship care. The testicular function will be compared to aged-matched controls from men attending the Family Planning Association for premarital check-up.
Eligibility
Inclusion Criteria3
- Men who have received chemotherapy and/ or radiotherapy for cancer diagnosed when they were \< 18 years old.
- \> 18 years old to 50 years old
- Cancer in remission for at least 2 years
Exclusion Criteria4
- Unable to ejaculate by masturbation to provide semen samples
- Cryptorchidism, testicular cancer, history of vasectomy
- On testosterone replacement therapy
- Refusal to join the study
Interventions
Blood for FSH, LH, testosterone
Semen analysis
The European Male Ageing Study (EMAS) questionnaire
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06587477