RecruitingNot ApplicableNCT06588777

Ultrasound Guided Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) Versus Quadratus Lumborum Block for Postoperative Analgesia in Laparoscopic Cholecystectomy


Sponsor

Ain Shams University

Enrollment

52 participants

Start Date

Sep 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to compare the efficacy of using Ultrasound guided modified thoracoabdominal nerve block through perichondrial approach (M-TAPA) versus quadratus lumborum block for postoperative analgesia in laparoscopic cholecystectomy under general anesthesia.


Eligibility

Min Age: 21 YearsMax Age: 71 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two different nerve block techniques (injections that numb the area) for controlling pain after laparoscopic gallbladder removal surgery. Both methods use ultrasound guidance, and neither involves general opioid medication — the goal is to find the better method for reducing post-surgery pain. **You may be eligible if...** - You are between 21 and 70 years old - You are scheduled for laparoscopic (keyhole) gallbladder removal surgery - You are in generally good or mild health (ASA class I or II) **You may NOT be eligible if...** - You refuse the procedure or study participation - You have a serious health condition (ASA class III or above) - You have a blood clotting disorder - You have a skin infection near the injection site - Your BMI is above 40 - You have a known allergy to local anesthetics Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREModified thoracoabdominal nerve block through perichondrial approach (M-TAPA)

transversus abdominis, internal oblique, and external oblique muscles will be identified with a high-frequency (10 MHz) linear probe on the costochondral angle in the sagittal plane under ultrasound guidance at the 10th costal margin. A deep angle was given to the costochondral angle at the edge of the 10th costal margin with the probe in the sagittal direction to view the lower surface of the costal cartilage in the midline. A 22-G, 100-mm block needle will be inserted in the cranial direction using the in-plane technique and the needle tip will be moved to the posterior aspect of the 10th costal cartilage. It is noted that the needle tip never crossed the cranial edge of the 10th costal cartilage

PROCEDUREQuadratus lumborum block

using ultrasound guidance (Sonosite turbo M, Bothell, Washington, USA) and a curved ultrasound probe (2.5-7.5 MHz). The probe will be placed in the mid-axillary line between the lower costal margin and the iliac crest in a transverse plane to view all abdominal layers. The probe will be moved towards the posterior axillary line, to reach a point where all three abdominal muscle layers merge to form aponeurosis. The aponeurosis will then be followed dorsally until the quadratus lumborum muscle is seen deep to transversalis fascia with its attachment to the transverse process of the L4 vertebral body. A 22 G, 100 mm, blunt, insulated nerve block needle will be inserted 1 cm medial to the probe and advanced using the in-plane technique with ultrasound real-time assessment. The injection site will be the junction of transversalis fascia and the anterolateral border of quadratus lumborum muscle


Locations(1)

Ainshams university hospitals

Cairo, Egypt

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NCT06588777


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