RecruitingNCT06594107

Factors for the Onset and Course of Axial Spondylitis

Faktorer För Uppkomst Och Förlopp Av Axial Spondylartrit


Sponsor

Karolinska Institutet

Enrollment

1,000 participants

Start Date

Sep 1, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

In a research project, investigators want to study the course of the disease of axial spondylitis: the causes of disease onset, prognosis, and treatment effects. The goal is to improve treatment and in the long run also prevention of the disease. The project has a focus on the body\'s own substance prostaglandin, and its proinflammatory role in spondylitis, but also other substances may be analyzed in blood and urine samples. The purpose of the research project is include newly diagnosed treatment-naive patients with axial spondyloarthritis, to follow them after 1 and 2 years after treatment start, to collect clinical data, questionnaires, blood and urinsamples to find blood or urine markers that can be used for precision therapy of axial spondylitis.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • newly diagnosed patients with axial spondyloarthritis
  • treatment-naive
  • years of age or older
  • Swedish-speaking
  • Able to give informed consent

Exclusion Criteria3

  • DMARD treatment,
  • ongoing infection
  • ongoing malignancy

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Locations(2)

Karolinska University Hospital

Huddinge, Stockholm County, Sweden

Center for Rheumatology Stockholm

Stockholm, Stockholm County, Sweden

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NCT06594107


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