Axial Spondyloarthritis Clinical Trials

29 recruitingLast updated: June 18, 2026

There are 29 actively recruiting axial spondyloarthritis clinical trials across 27 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 4, Phase 3. Top locations include Berlin, Germany, Upland, California, United States, Beijing, Beijing Municipality, China. Updated daily from ClinicalTrials.gov.


Axial Spondyloarthritis Trials at a Glance

29 actively recruiting trials for axial spondyloarthritis are listed on ClinicalTrialsFinder across 6 cities in 27 countries. The largest study group is Not Applicable with 9 trials, with the heaviest enrollment activity in Berlin, Upland, and Beijing. Lead sponsors running axial spondyloarthritis studies include Assistance Publique - Hôpitaux de Paris, Charite University, Berlin, Germany, and The Danish Center for Expertise in Rheumatology.

Browse axial spondyloarthritis trials by phase

Treatments under study

About Axial Spondyloarthritis Clinical Trials

Looking for clinical trials for Axial Spondyloarthritis? There are currently 22 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Axial Spondyloarthritis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Axial Spondyloarthritis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 29 trials

Recruiting
Phase 2

A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)

Radiographic Axial Spondyloarthritis
Merck Sharp & Dohme LLC315 enrolled100 locationsNCT07133633
Recruiting
Not Applicable

Physical Activity Through Health Technology in Axial Spondyloarthritis

Axial Spondyloarthritis
University of Washington40 enrolled2 locationsNCT07642622
Recruiting
Phase 1

A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults

Psoriatic ArthritisAxial Spondyloarthritis
UCB Biopharma SRL392 enrolled61 locationsNCT07290036
Recruiting
Phase 1Phase 2

EAST-1 (ERAP-inhibition in Axial Spondyloarthritis Trial - 1)

Axial Spondyloarthritis (AxSpA)
Grey Wolf Therapeutics141 enrolled15 locationsNCT07047703
Recruiting
Phase 2

A Study of SPY072 in Rheumatic Disease

Rheumatoid ArthritisPsoriatic ArthritisRheumatic Diseases+5 more
Spyre Therapeutics, Inc.285 enrolled64 locationsNCT07148414
Recruiting
Phase 1

A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)

Hidradenitis SuppurativaPsoriatic ArthritisAxial Spondyloarthritis+1 more
UCB Biopharma SRL20 enrolled12 locationsNCT06888193
Recruiting
Phase 4

Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases

Psoriatic Arthritis (PsA)Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)+9 more
University of Sao Paulo General Hospital477 enrolled2 locationsNCT07087912
Recruiting

The Disease Progression of Chinese Axial Spondyloarthritis in a Real-word Cohort Study

Ankylosing Spondylitis (AS)Axial Spondyloarthritis
China-Japan Friendship Hospital2,250 enrolled1 locationNCT06844643
Recruiting

A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease

Celiac DiseaseMultiple SclerosisAnkylosing Spondylitis+6 more
TScan Therapeutics, Inc.300 enrolled12 locationsNCT06587828
Recruiting
Not Applicable

Effects of Yoga Therapy in Rehabilitation Compared to Physiotherapy in Moderate Axial Spondyloarthritis (axSPA)

Axial Spondyloarthritis (AxSpA)
Assistance Publique - Hôpitaux de Paris72 enrolled5 locationsNCT06083090
Recruiting
Phase 4

REDO-JAK: Dose Reduction of Janus Kinase Inhibitors in Patients With Inflammatory Rheumatic Diseases

Psoriatic Arthritis (PsA)Rheumatoid Arthritis (RA)Axial Spondyloarthritis (AxSpA)
Sint Maartenskliniek200 enrolled7 locationsNCT07160231
Recruiting
Not Applicable

INSELMA - a Randomised Controlled Trial

Rheumatoid ArthritisPsoriatic ArthritisAxial Spondyloarthritis
The Danish Center for Expertise in Rheumatology120 enrolled3 locationsNCT06583980
Recruiting
Phase 3

A Trial of SHR-1314 Injection in Adult Patients With Active Non-radiographic Axial Spondyloarthritis

Active Non-radiographic Axial Spondyloarthritis
Suzhou Suncadia Biopharmaceuticals Co., Ltd.380 enrolled1 locationNCT06860750
Recruiting
Not Applicable

Optimizing Anti-IL17 Antibody Therapy by Associating Fiber Supplementation to Correct Treatment-aggravated Gut Dysbiosis in Axial Spondyloarthritis - RESPOND-IL17

Axial Spondyloarthritis
Centre Hospitalier Universitaire de Nīmes36 enrolled3 locationsNCT05812157
Recruiting
Not Applicable

Taekwondo for Axial Spondyloarthritis

Ankylosing SpondylitisAxial Spondyloarthritis
Wonju Severance Christian Hospital24 enrolled1 locationNCT06823726
Recruiting
Phase 2

A Study to Evaluate 608 in Patients With Non- Radiographic Axial Spondyloarthritis (Nr-axSpA)

Axial Spondyloarthritis
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.180 enrolled6 locationsNCT06222671
Recruiting

A LONGITUDINAL OBSERVATIONAL STUDY to EVALUATE the EFFICACY of MOVEMENT and IMPLEMENT CONCRETE MOVEMENT RECOMMENDATIONS with the HELP of MOBILITY TRACKING with SMARTWATCHES in SUBJECTS with AXIAL SPONDYLOARTHRITIS

Axial SpondyloarthritisAxial Spondyloarthritis (AxSpA)Axial Spondyloarthritis, Non-Radiographic+4 more
University of Bonn50 enrolled1 locationNCT06807853
Recruiting
Phase 4

ToFAcitinib in Early Active Axial SpondyloarThritis:

Axial Spondyloarthritis
Charite University, Berlin, Germany104 enrolled1 locationNCT06112665
Recruiting
Not Applicable

WORK-ON Vocational Rehabilitation for People with Inflammatory Arthritis

Rheumatoid ArthritisPsoriatic ArthritisAxial Spondyloarthritis
The Danish Center for Expertise in Rheumatology56 enrolled1 locationNCT06299917
Recruiting

Factors for the Onset and Course of Axial Spondylitis

Axial Spondyloarthritis
Karolinska Institutet1,000 enrolled2 locationsNCT06594107