Differential Assessment of Hypertonia
Differential Assessment of Hypertonia Related to CNS Impairment
Chang Gung University
45 participants
Oct 9, 2024
INTERVENTIONAL
Conditions
Summary
Spasticity and rigidity are common symptoms of central nervous system injuries, such as spinal cord injury and Parkinson's disease, and result in distinct patterns of increased resistance during passive joint movements. Spasticity is characterized by a velocity-dependent increase in stretch reflexes, accompanied by exaggerated tendon responses, while rigidity is marked by consistent resistance throughout the range of motion, traditionally considered independent of stretch velocity. However, recent studies suggest that rigidity may also be influenced by stretch velocity. This study aims to investigate muscle tone by examining spasticity, rigidity, and normal muscle function through neural and biomechanical changes. Standard clinical tools, such as the Modified Ashworth Scale and Unified Parkinson's Disease Rating Scale, along with additional assessments like the Myoton and Post-Activation Depression (PAD), will be employed.
Eligibility
Inclusion Criteria2
- Health subjects:
- \- Clinical diagnosis of Parkinson disease.
Exclusion Criteria13
- Musculoskeletal injuries on legs.
- Osteoporosis.
- SCI subjects:
- Current musculoskeletal or joint injuries in the lower limbs.
- History of central or peripheral neuromuscular diseases.
- Presence of a pacemaker.
- Current use of antispastic or antidepressant medications.
- Current venous thromboembolism or osteoporosis.
- Impairment of the soleus H-reflex arc.
- PD subjects:
- Musculoskeletal injuries on legs
- Osteoporosis.
- Any peripheral or central nervous system injury or disease patients.
Interventions
Continuous passive motion device (CPM) of ankle at 1HZ(60rpm) for 10 repetitions
Continuous passive motion device (CPM) of ankle 0.25HZ (15rpm) for 10 repetitions
Locations(1)
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NCT06596187