RecruitingNot ApplicableNCT06599372

Evaluation of the Efficacy of Transcranial Magnetic Stimulation on Resistant Auditory Hallucinations in Schizophrenia

Treatment of Resistant Auditory Hallucinations in Schizophrenia by Repetitive Transcranial Magnetic Stimulation. Naturalistic Study


Sponsor

Dominique JANUEL

Enrollment

30 participants

Start Date

Jul 11, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

This open naturalistic study aims to evaluate the efficacy of rTMS in routine practice on auditory resistant hallucinations (AHR) of patients with schizophrenia. To this end, two stimulation methods will be offered to patients: the rTMS stimulation method and the cTBS stimulation method.We principally use the AHRS scale to evaluate the effectiveness of rTMS on RAH in patients with schizophrenia. Our main hypothesis is that rTMS used under naturalistic conditions, in addition to antipsychotics, would allow a relative improvement of resistant auditory hallucinations assessed by the AHRS scale between baseline and end of treatment in patients with schizophrenia.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether transcranial magnetic stimulation (TMS) — a non-invasive treatment that uses magnetic pulses to stimulate specific brain areas — can reduce persistent hearing voices (auditory hallucinations) in people with schizophrenia whose symptoms haven't improved with standard medications. **You may be eligible if...** - You are 18 or older - You have been diagnosed with schizophrenia - You continue to hear voices despite trying at least two different antipsychotic medications - You are able to communicate in French - Women of childbearing age must be using contraception and have a negative pregnancy test **You may NOT be eligible if...** - You have metal in your skull, uncontrolled epilepsy, or a cochlear implant (these are safety risks for magnetic stimulation) - You have an unstable medical condition - You are pregnant or breastfeeding - You are currently enrolled in another research study - You are a minor Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERThe rTMS method

The patient receives treatment under naturalistic conditions in routine practice.

OTHERThe cTBS method

The patient receives the treatment under naturalistic conditions in routine practice.


Locations(1)

Etablissement Public de Santé de Ville-Evrard

Neuilly-sur-Marne, France

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NCT06599372


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