Postoperative Radiotherapy for Intermediate- and High-risk Patients With HNSCC Greater Than 6 Weeks After Surgery

This study examines whether starting radiation therapy more than 6 weeks after head and neck cancer surgery affects treatment outcomes for patients with intermediate or high-risk disease. Current guidelines recommend starting radiation within 6 weeks, but delays often happen — this study aims to understand the real-world impact. **You may be eligible if...** - You have been diagnosed with squamous cell carcinoma (a type of cancer) of the mouth, throat, voice box, sinuses, or neck lymph nodes - Your cancer has specific risk features that require post-surgery radiation (such as large tumor size, spread to multiple lymph nodes, nerve or vascular invasion, or close surgical margins) - Your radiation is intended to cure the cancer, not just control it **You may NOT be eligible if...** - You do not have the required high-risk pathological features - Your radiation is not being given with curative intent Talk to your doctor to see if this trial is right for you.