RecruitingNot ApplicableNCT06609200

Electro-Acupuncture for Obese Patients With Insulin Resistance

Electro-acupuncture for the Obese Patient With Insulin Resistance: a Randomized Sham-controlled Clinical Trial


Sponsor

Nanyang Technological University

Enrollment

60 participants

Start Date

Oct 10, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This clinical trial aims to evaluate the efficacy and safety of electro-acupuncture for obese patients with insulin resistance. 60 participants will be randomized and allocated to either the electro-acupuncture arm or the sham acupuncture arm.


Eligibility

Min Age: 21 YearsMax Age: 65 Years

Inclusion Criteria4

  • Men and women aged between 21 and 65 years old
  • BMI ≥ 25 kg/m2
  • HOMA-IR ≥ 2.14, (HOMA-IR = fasting insulin (ųU/mL)* fasting glucose (mmol/L)/22.5)
  • Not receiving any other weight control measures or any medical and/or drug history in the last 3 months

Exclusion Criteria10

  • Diabetes mellitus
  • Treating with drugs that may affect insulin sensitivity
  • Changes 10% of usual body weight in the previous 6 months weight
  • Endocrine diseases, including thyroid disorder, pituitary disorder, sex gland disorder, etc.
  • Heart diseases, including arrhythmia, heart failure, and myocardial infarction, participants with pacemakers
  • Allergy and immunology diseases
  • Bleeding tendency
  • Pregnant or lactating women
  • Impaired hepatic or renal function
  • Stroke or unable to exercise

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Interventions

DEVICEAcupuncture needles

The acupuncture needles and related equipment will have already received approval for routine Traditional Chinese Medicine (TCM) clinical practice in Singapore.


Locations(1)

Nanyang Technological University Traditional Chinese Medicine Clinic

Singapore, Singapore

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NCT06609200


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