Safety and Efficacy of Pramipexole Treatment in Resistant Obsessive-Compulsive Disorder (OCD)

This study tests whether pramipexole — a medication normally used for Parkinson's disease — can help people with obsessive-compulsive disorder (OCD) who haven't responded well to standard treatments. OCD causes repeated, unwanted thoughts and the urge to perform rituals, and some cases are very hard to treat. **You may be eligible if...** - You are between 18 and 64 years old - Your native language is European Portuguese - You have been diagnosed with OCD - Your OCD symptoms are severe (score of 16 or higher on the standard OCD rating scale) - You have tried at least one standard OCD treatment (like an SSRI) without enough improvement **You may NOT be eligible if...** - You have a history of bipolar disorder or psychosis - You are pregnant or breastfeeding - You have certain heart conditions or other medical problems that make the medication unsafe - You are currently taking medications that could interact with pramipexole Talk to your doctor to see if this trial is right for you.