Serum Calprotectin in Surgical Septic Patients
Serum Calprotectin in Surgical Septic Patients as an Early Predictor of Clinical Severity and Mortality: a Prospective Comparative Study.
Azienda Ospedaliero, Universitaria Pisana
150 participants
Nov 1, 2021
OBSERVATIONAL
Conditions
Summary
To early evaluate the serum levels of calprotectin in patients suffering from intra-abdominal sepsis requiring a surgical treatment. The research project aims to investigate the role of serum calprotectin in the diagnosis of sepsis and to establish whether its level significantly correlates with different degree of disease severity and with short and long-term outcomes. If these associations were confirmed, serum calprotectin would represent an easily and rapidly detectable biomarker able to predict the severity of sepsis.
Eligibility
Inclusion Criteria5
- diagnosis of upper/lower gastro-intestinal perforation
- diagnosis of intestinal occlusion
- diagnosis of acute cholecystitis
- diagnosis of complicated acute appendicitis
- radiological diagnosis of intra-abdominal sepsis
Exclusion Criteria4
- recent (<3 months) surgery
- recent (<3 months) trauma
- diagnosis of acute pancreatitis
- diagnosis of burn
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Interventions
A blood sample is collected at time of admission to detect serum level of calprotectin
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06614088