Tennessee Alzheimer's Project

This is the Tennessee Alzheimer's Project, a research study that follows adults aged 60 and older to better understand the early stages of Alzheimer's disease and cognitive decline. Participants will undergo brain imaging, memory testing, and blood draws over several years. **You may be eligible if...** - You are 60 or older - You are cognitively unimpaired, have mild cognitive impairment, or have been diagnosed with Alzheimer's disease - You speak English - You can make your own decisions about participating - You have a reliable study partner (someone who knows you well and can attend some visits) **You may NOT be eligible if...** - You have no study partner available - You have a history of serious psychiatric illness (schizophrenia, bipolar disorder), neurological illness (epilepsy, Parkinson's disease, multiple sclerosis), or significant head injury - You cannot have an MRI (e.g., due to claustrophobia or metal in your body) Talk to your doctor to see if this trial is right for you.