RecruitingNot ApplicableNCT06616649

Closed Loop Spinal Cord Stimulation for Chemotherapy Induced Peripheral Neuropathy, a Pilot Study.

Sponsor

M.D. Anderson Cancer Center

Enrollment

10 participants

Start Date

Jul 14, 2025

Study Type

INTERVENTIONAL

Conditions

Peripheral Neuropathy Due to Chemotherapy

Summary

To explore the benefits of using closed loop spinal cord stimulation (SCS) in the treatment of patients experiencing painful chemotherapy induced peripheral neuropathy (CIPN) by assessing changes in pain, quality of life, pain medication use, sensory improvement through quantitative sensory testing, and improvement of gait through quantitative gait testing.

Eligibility

Min Age: 18 Years

Inclusion Criteria4

Age ≥18 years
Diagnosis history of CIPN of lower extremities
Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of SCS
Ability to understand and the willingness to sign a written informed consent document.

Exclusion Criteria8

Patients undergoing active chemotherapy or immunotherapy
Patients undergoing medical litigation.
Patients with active infection, being treated with antibiotics
Patients that are pregnant or planning to conceive
Patients who are receiving any investigational agents.
Patients with brain metastases.
Patients with cognitive impairment/psychiatric illness/social situations that would limit compliance with study requirements.
Patients with history of alternative forms of sensorimotor neuropathies prior to CIPN presentation