RecruitingEarly Phase 1NCT06744816
Exploring the Benefit of Topical Capsaicin in Treating Pain From Chemo-induced Peripheral Neuropathy: a Longitudinal Single Center Pilot Study
Sponsor
M.D. Anderson Cancer Center
Enrollment
20 participants
Start Date
Dec 11, 2025
Study Type
INTERVENTIONAL
Conditions
Summary
To learn if topical capsaicin can help relieve pain from CIPN and improve gait (the pattern of walking) in patients.
Eligibility
Min Age: 18 Years
Inclusion Criteria4
- Participants diagnosed with pain of the lower extremity from chronic (>90 days duration) CIPN (due to either vinca alkaloids, taxanes, bortezomib, thalidomide, platinum-based compounds), seen at MD Anderson Cancer Center
- Participants reporting baseline pain ≥ 4 (0-10 scale, NRS)
- Participants age 18+
- Participants who have completed chemotherapy within the last year at the time of enrollment.
Exclusion Criteria5
- Participants with cognitive dysfunction
- Participants with recent history (<6 months) of drug or alcohol abuse
- Participants with open skin lesion or undergoing antibiotic therapy for local for systemic infection
- Participants with allergies to capsaicin or adhesives
- Pregnant participants
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Interventions
DRUGQutenza Patch
Given topical
Locations(1)
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NCT06744816
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