Use of Sodium Bicarbonate As Prophylaxis for Kidney Damage in Patients with Heatstroke
Hospital General de Mexicali
1 participants
May 1, 2024
INTERVENTIONAL
Conditions
Summary
This study protocol aims to prevent the need for renal replacement therapy in patients with rhabdomyolysis secondary to heatstroke. It is based on previous studies showing that bicarbonate infusion reduces renal failure in similar contexts. The intervention will be conducted at the General Hospital of Mexicali during the summer, targeting the prevention of renal failure and reducing the necessity for renal replacement therapy.
Eligibility
Inclusion Criteria4
- Admitted to the General Hospital of Mexicali with the diagnosis of heat stroke.
- Meeting the operational definition (exposure to heat, body temperature at admission greater than 40 degrees Celsius).
- CPK level greater than 1000 U/L.
- Having informed consent from the patient or the legally responsible adult.
Exclusion Criteria2
- Exclusion of the heat stroke diagnosis during their evaluation.
- Lack of serum creatinine levels at the time of admission to the protocol.
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Interventions
This group will receive 100 mEq of sodium bicarbonate diluted in one liter of saline solution, administered at a rate of 100 ml/h, with the goal of maintaining a urinary pH greater than 6.5.
The usual management for heat stroke will be given to this group
Locations(1)
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NCT06622525