Therapy Evaluation in Patients With Minor Stroke and Large Vessel Occlusion
Therapy Evaluation in Patients With Minor Stroke and Large Vessel Occlusion: A Prospective Multicenter Registry Study
Sir Run Run Shaw Hospital
200 participants
Nov 22, 2021
OBSERVATIONAL
Conditions
Summary
This multicenter registry study, which record the therapy strategy and follows up these acute ischemic stroke (AIS) patients with low NIHSS and large vessel occlusion (LVO), is intended to provide the important data for therapy evaluation and prognostic prediction of the LVO patients with low NIHSS.
Eligibility
Inclusion Criteria5
- Aged 18 years or older
- Acute ischemic stroke patients of NIHSS 0-5 with 24 hours after onset
- Proximal intracranial artery occlusion on NCCT/CTA or MRI/MRA showing occlusion of the intracranial ICA, M1, or proximal M2 vessel
- Baseline ASPECTS ≥6 or infarct Core Volume of < 70 on NCCT/DWI/CTP
- Pre-mRS≤1
Exclusion Criteria4
- Any sign of intracranial hemorrhage on baseline CT/MR;
- Seizures at stroke onset
- Baseline blood glucose of <2.78 mmol or >22.20 mmol, or platelet count < 100,000/uL or serum creatinine levels > 3.0 mg/dL
- Participation in any investigational study in the previous 30 days
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Interventions
The best medical therapy includes intravenous fibrinolysis, anticoagulants or antiplatelet, but NOT any immediate endovascular therapies.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06633809