RecruitingNot ApplicableNCT06635538

One-shot Ovarian Stimulation Protocol (One-shot)

One-Shot Ovarian Stimulation Protocol: A Pilot Study Investigating the Endocrine Profile


Sponsor

Fundación Santiago Dexeus Font

Enrollment

20 participants

Start Date

Oct 31, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The current prospective observational pilot study aims to evaluate the endocrine profile of a single-injection protocol (single CFA + daily oral administration of CC).


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Clomiphene Citrate (CC) 100 mg/day from D1, a drug called Corifollitropin alfa (CFA) 150 mcg + Clomiphene Citrate (CC) 100 mg/day from D1, and others for people with infertility, female. The study is currently recruiting participants at 3 locations. People eligible for this study include women aged 18 Years to 40 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGCorifollitropin alfa (CFA) 150 mcg + Clomiphene Citrate (CC) 100 mg/day from D1

On day 2 or 3 of the menstrual cycle or after 5 days of pill-free interval, a single injection of 150 mcg of CFA (Stimulation Day 1) will be administered.

DRUGClomiphene Citrate (CC) 100 mg/day from D1

On day 2 or 3 of the menstrual cycle or after 5 days of pill-free interval, the patients will start oral administration of Clomiphene Citrate 100/day continuing up to and including the day of ovulation triggering

DIAGNOSTIC_TESTMonitoring cycle

Scan controls and blood exams will be performed on stimulation days 1, 6, 8, 10 and, according to clinical needs, until trigger day.


Locations(3)

Dexeus Mujer Sabadell

Sabadell, Barcelona, Spain

Dexeus Mujer Sant Cugat

Sant Cugat del Vallès, Barcelona, Spain

Departamento de Ginecología Obstetricia y Reproducción. Hospital Universitari Dexeus

Barcelona, Spain

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NCT06635538


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