Personalized ViscoElastic Testing-guided Bleeding Management In Liver Surgery, Neurosurgery and Obstetrics
Personalized ViscoElastic Testing-guided Bleeding Management In Liver Surgery, Neurosurgery and Obstetrics - a Prospective Comparison of the Novel ClotPro With ROTEM and TEG
Medical University of Vienna
240 participants
Jul 1, 2024
OBSERVATIONAL
Conditions
Summary
The ClotPro analyzer is a new generation viscoelastic analyzer for the in vitro assessment of blood coagulation. This study aims to assess the agreement of ClotPro 6.0, ROTEM delta, and TEG 6s in three distinct cohorts: i) patients with liver disease undergoing liver surgery, ii) pregnant women undergoing elective cesarean section, and iii) patients undergoing elective intracranial neurosurgery. Further coagulation tests will be performed (standard laboratory coagulation tests, thrombin and plasmin generation tests) in an exploratory fashion to compare them with viscoelastic test results. The obtained test results will not result in any diagnostic or therapeutic consequences for patients included in this study.
Eligibility
Inclusion Criteria7
- Vulnerable patient cohorts
- Patients undergoing elective liver surgery defined as one of the following invasive procedures:
- Liver resection (anatomic or non-anatomic segmental resection, right or left hepatectomy, right or left extended hepatectomy),
- Orthotopic liver transplantation,
- Pregnant women undergoing an elective caesarean section, and
- Patients undergoing an elective intracranial neurosurgery.
- Written informed consent
Exclusion Criteria1
- none
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Interventions
viscoelasting testing refers to a global hemostatic assay,that quantifies the viscoelastic properties of citrated whole blood
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06635564