RecruitingNot ApplicableNCT06642649

Evaluation and Comparison Between General Anesthesia VS Two Types of Combined Anesthesia for Opioid Consumption in Laparoscopic Hysterectomy

Evaluation and Comparison Between General Anesthesia VS Two Types of Combined Anesthesia (general and Spinal Anesthesia) for Opioid Consumption in Laparoscopic Hysterectomy: a Multi-Center, Randomized, Prospective, Controlled Trial


Sponsor

Andrea Saporito

Enrollment

45 participants

Start Date

Nov 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of the study is to evaluate and compare general anesthesia VS two types of combined anesthesia in opioid consumption after laparoscopic hysterectomy


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria2

  • patients over 18 year of age,
  • ASA physical status I to III scheduled for laparoscopic hysterectomy (with or without adnexectomy)

Exclusion Criteria10

  • patients with inability to consent,
  • patient refusal,
  • contraindication to spinal anesthesia (e.g., hemodynamic instability, infection at the surgery site, and neurologic defects such as transverse myelitis, coagulopathies or ongoing anticoagulant therapy),
  • known chronic pain syndrome, known
  • suspected non- compliance,
  • drug, or alcohol abuse ,
  • major oncological surgeries,
  • allergy to drugs used in the protocol,
  • previous chronic use of analgesics
  • history of opioid abuse

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Interventions

PROCEDUREGeneral Anesthesia (control group)

Only General Anestesia

PROCEDUREGeneral Anesthesia + Spinal anesthesia combined (local anesthetic, morfine and no fentanyl)

General anesthesia + spinal anesthesia with local anesthetic and morfine

PROCEDUREGeneral Anesthesia + Spinal anesthesia combined (local anesthetic, morfine and 20 mcg fentanyl)

General anesthesia + spinal anesthesia with local anesthetic, morfine and fentanyl


Locations(2)

Ente Ospedaliero Cantonale ORBV

Bellinzona, Switzerland, Switzerland

Ente Ospedaliero Cantonale, Ospedale Regionale di Bellinzona e Valli

Bellinzona, Switzerland, Switzerland

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NCT06642649


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