RecruitingNCT06643741

Non-Invasive Preeclampsia Screening and Biobank

Collection of Pregnancy Outcome Data and Whole Blood Samples From Women Undergoing Non-Invasive Screening for Early, Preterm, and Term Preeclampsia


Sponsor

Sequenom, Inc.

Enrollment

6,550 participants

Start Date

Feb 2, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Women pregnant between 11-14 weeks gestation will be enrolled with blood samples collected to evaluate for preeclampsia.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria7

  • Subject is female and 18 years of age and older;
  • Subject provides a signed and dated informed consent;
  • Subject is pregnant with a singleton pregnancy at ≥11.0 - ≤14.0 weeks' gestation;
  • Subject agrees to provide the Sponsor access to any prenatal and postnatal screening or diagnostic test results and supporting data;
  • Subject agrees to have UtAPI calculated during their SOC first trimester ultrasound and MAP collected at the first trimester SOC visit;
  • Subject agrees to provide up to 25mL of whole blood at each trimester visit;
  • Subject agrees to provide relevant medical and pregnancy/postnatal information including outcome.

Exclusion Criteria4

  • Subject is unlikely to return for second and third trimester testing;
  • Subject is unlikely to have pregnancy outcome data available;
  • Previous sample donation under this protocol with the same pregnancy;
  • Subject is participating in a blinded aspirin study or taking unknown doses of aspirin.

Locations(21)

Valley Perinatal

Glendale, Arizona, United States

Delaware Center for Maternal and Fetal Medicine

Newark, Delaware, United States

D&H National Research Centers

Miami, Florida, United States

Southern Clinical Research Associates

Metairie, Louisiana, United States

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States

Cooper University Health Care

Camden, New Jersey, United States

New Jersey Perinatal Associates

Livingston, New Jersey, United States

Rutgers Robert Wood Johnson Medical School

New Brunswick, New Jersey, United States

Capital Health

Pennington, New Jersey, United States

Columbia University Medical Center

New York, New York, United States

Lenox Hill Hospital

New York, New York, United States

Wake Forest University Health Sciences

Winston-Salem, North Carolina, United States

Geisinger Medical Center

Danville, Pennsylvania, United States

University of Pennsylvania Perelman School of Medicine

Philadelphia, Pennsylvania, United States

Lewis Katz School of Medicine at Temple University

Philadelphia, Pennsylvania, United States

Chattanooga Medical Research

Chattanooga, Tennessee, United States

St. David's Women's Center of Texas

Austin, Texas, United States

University of Texas Medical Branch

Galveston, Texas, United States

UT Health

Houston, Texas, United States

HCA Healthcare, Texas Maternal Fetal Medicine

Houston, Texas, United States

Macon & Joan Brock Virginia Health Sciences at Old Dominion University

Norfolk, Virginia, United States

View Full Details on ClinicalTrials.gov

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NCT06643741


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