Family Members At INcreased-risk for Developing Inflammatory Bowel Disease
Family Members At INcreased-risk for Developing Inflammatory Bowel Disease (FIND-IBD)
Massachusetts General Hospital
50 participants
Dec 18, 2024
OBSERVATIONAL
Conditions
Summary
First-degree relatives of people with inflammatory bowel disease ("IBD," including Crohn's disease and ulcerative colitis) have an increased risk for developing IBD themselves. This study will follow unaffected first-degree relatives (who do not have IBD) over time to understand if their behaviors, diet, and biomarkers for IBD can help predict who gets IBD and if IBD can be prevented in these high-risk individuals. Participants will be asked once per year to complete a questionnaire and have their blood, stool, and urine collected. The anticipated length of the study (registry) is approximately 10 years or longer. Parts of this study, such as the questionnaires and stool and urine collection, may be done from home, while other parts, such as the blood draw, will need to be done from Massachusetts General Hospital.
Eligibility
Inclusion Criteria5
- Ability to give informed consent
- Ability to complete all study visits and study-related procedures
- Ability to understand and complete study questionnaires
- Must have at least one first-degree relative with inflammatory bowel disease (Crohn's disease, ulcerative colitis, or IBD-unclassified)
- Age ≥ 14
Exclusion Criteria2
- Individuals with existing diagnoses of inflammatory bowel disease (ulcerative colitis, Crohn's disease, or IBD-unclassified)
- Evidence of clinical signs or symptoms of IBD, which will be identified on pre-screening interview with the study coordinator.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06655415