RecruitingNot ApplicableNCT06665373

Fitness and Nutrition in Glioma

A Pilot Study to Investigate the Effects of Combining a Modified Atkins Diet With a Physical Fitness Regimen in Patients Diagnosed With Malignant Glioma


Sponsor

NYU Langone Health

Enrollment

15 participants

Start Date

Oct 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This is a pilot study assessing the effects of combining a modified Atkins diet with a physical fitness regimen in patients with malignant glioma. A sample size of 15 participants will be enrolled in a 15-week program consisting of two weekly supervised exercise sessions combined with an individualized home exercise program and a modified Atkins diet.


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria4

  • Tissue confirmed diagnosis of high-grade glioma (World Health Organization grade III or IV)
  • Karnofsky Performance Status (KPS) ≥ 70%
  • Willing to follow the study intervention and follow-up
  • Able to give full informed consent

Exclusion Criteria6

  • Currently undergoing initial concurrent radiation/chemotherapy
  • Severe medical co-morbidities
  • Any medical condition which prohibits moderate to vigorous physical activity (60-85% HRmax)
  • Any medical condition which prohibits a restrictive diet
  • Neurological deficit preventing participation in moderate to vigorous physical activity
  • Severe psychiatric illness

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Interventions

BEHAVIORALModified Atkins Diet

The Atkins diet is a low-carb eating plan that focuses on balancing protein, fat, and carbohydrates.

BEHAVIORALFitness Program

12 weeks of two weekly supervised exercise sessions combined with an individualized home exercise program based on physical capabilities and available equipment.


Locations(1)

NYU Langone Health

New York, New York, United States

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NCT06665373


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