RecruitingNot ApplicableNCT06674252

A Study on the Improvement of Postoperative Symptoms and Survival Benefits of Modified Bufei Decoction in Elderly Patients With Lung Cancer Undergoing Radical Surgery

A Randomized Controlled Multicenter Study on the Improvement of Postoperative Symptoms and Survival Benefits of Modified Bufei Decoction in Elderly Patients With Lung Cancer Undergoing Radical Surgery

Sponsor

Peking University Cancer Hospital & Institute

Enrollment

174 participants

Start Date

Jun 13, 2025

Study Type

INTERVENTIONAL

Conditions

Lung Cancers

Summary

This is a randomized double-blind placebo-controlled phase II clinical study that included patients with symptoms such as cough, shortness of breath, and fatigue after lung cancer resection surgery. They were given orally modified Bufei Tang granules twice a day for 28 days, with one packet taken orally with water. Using the MDASI-TCM symptom scoring system, evaluate the scores of symptoms such as cough, shortness of breath, and fatigue before and after the experiment, and calculate the difference in scores between the control group and the experimental group before and after the experiment.

Eligibility

Min Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a Traditional Chinese Medicine herbal formula called Modified Bufei Decoction in elderly lung cancer patients who have had surgery to remove their tumor. Researchers want to see if this herbal remedy can reduce common post-surgery symptoms like cough, fatigue, and shortness of breath, and whether it improves long-term outcomes. **You may be eligible if...** - You are 65 years or older with a confirmed diagnosis of lung cancer after surgery - You experience at least moderate levels of cough, fatigue, or shortness of breath - Your heart function is essentially normal and your liver and kidney tests are within safe ranges - A Traditional Chinese Medicine assessment confirms a pattern of lung and kidney deficiency **You may NOT be eligible if...** - You have a severe lung infection - You have a diagnosed mental illness or depression - You are unable to take oral herbal medications Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERJiawei Bufei Tang granules

Jiawei Bufei Tang is a traditional Chinese medicine formula applied by Professor Li Pingping to patients with lung cancer and qi yin deficiency syndrome. It consists of Huangqi, Codonopsis pilosula, Schisandra chinensis, Rehmannia glutinosa, Ziyuan, Mulberry bark, Snake berry, Half branch Lotus, White Hedyotis diffusa, etc. Bu Fei Tang is derived from the Yuan Dynasty's "Yong Lei Ling Fang" and consists of six ingredients: ginseng, astragalus, schisandra, Radix Rehmanniae, Ziyuan, and mulberry bark. It is mainly used to treat cough caused by lung qi deficiency. Jiawei Bufei Tang adds white Hedyotis diffusa, Scutellaria barbata, and snake berry to the original formula. White Hedyotis diffusa is more effective in dispelling carbuncles and detoxifying, Scutellaria barbata is more effective in dispelling phlegm and diuresis, and snake berry is more effective in dispelling scrofula and dispersing nodules, increasing the effect of clearing heat and detoxifying. This formula is particularly e

DRUGPlacebo

placebo

Locations(2)

Beijing cancer hospital

Beijing, Beijing Municipality, China

Beijing cancer hospital

Beijing, Beijing Municipality, China

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NCT06674252

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