RecruitingNCT06680180

Fibrinolysis Resistance in Infection and Trauma


Sponsor

Anders Aneman

Enrollment

150 participants

Start Date

Jun 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Blood coagulation disorders are often seen in critically ill patients e.g. with severe infection or following extensive injury, that can lead to life threatening events as a result of excessive blood clot formation leading to organ failure. This study aims to use Viscoelastic Testing (VET) technology to detect patients at risk of excessive blood blot formation at the bedside, test new blood coagulation drugs, and guide life-saving use of blood modifying treatments.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Viscoelastometric assessment of fibrinolysis for people with sepsis and septic shock and trauma. The study is currently recruiting participants at 4 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTViscoelastometric assessment of fibrinolysis

Viscoelastometric assessment of whole blood fibrinolysis using supplemental tissue plasminogen activator (tPA) and other agents ex vivo to influence fibrinolysis capacity.


Locations(4)

The Canberra hospital (ICU)

Canberra, Australian Capital Territory, Australia

Liverpool Hospital (ICU)

Liverpool, New South Wales, Australia

Macquarie University Hospital (ICU)

Macquarie, New South Wales, Australia

Royal North Shore Hospital (ICU)

St Leonards, New South Wales, Australia

View Full Details on ClinicalTrials.gov

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NCT06680180


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