Fibrinolysis Resistance in Infection and Trauma
Anders Aneman
150 participants
Jun 1, 2024
OBSERVATIONAL
Conditions
Summary
Blood coagulation disorders are often seen in critically ill patients e.g. with severe infection or following extensive injury, that can lead to life threatening events as a result of excessive blood clot formation leading to organ failure. This study aims to use Viscoelastic Testing (VET) technology to detect patients at risk of excessive blood blot formation at the bedside, test new blood coagulation drugs, and guide life-saving use of blood modifying treatments.
Eligibility
Plain Language Summary
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Interventions
Viscoelastometric assessment of whole blood fibrinolysis using supplemental tissue plasminogen activator (tPA) and other agents ex vivo to influence fibrinolysis capacity.
Locations(4)
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NCT06680180