RecruitingNCT06687291

Cognitive Impact Associated With Surgery For Gastric Or Esophageal Cancer

Sponsor

Karolinska Institutet

Enrollment

130 participants

Start Date

Feb 13, 2025

Study Type

OBSERVATIONAL

Conditions

Sarcopenia Quality of Life (QOL)Chemotherapy Depression Gastroesophageal Cancer (GC)Frailty Malnutrition Postoperative Delirium (POD)Chemobrain

Summary

The primary objective of this observational study is to investigate the incidence of Post Operative Delirium (POD) after gastroesophageal cancer surgery. Secondary objectives are to investigate the relationship between POD, preoperative depression, frailty, quality of life, malnutrition and sarcopenia. Participants identified with POD will be asked (at the routine follow-up meeting after surgery) to participate in an qualitative interview, in order to understand the participant's experience of postoperative delirium. The main objective aims to answer: What is the incidence of POD after gastroesophageal cancer surgery.

Eligibility

Min Age: 18 Years

Inclusion Criteria4

Patients diagnosed with esophageal or gastric cancer, treated with (or without) chemotherapy and surgery.
Age ≥18 at the time for inclusion.
Participate on a voluntary basis and can (for any reason) end its participation during the study.
Capable of giving informed consent.

Exclusion Criteria5

Patients with preoperative cognitive dysfunction such as dementia.
Patients who are inoperable due to metastases.
Patients unable to communicate due to severely impaired hearing and/or - seeing.
Patients with ongoing drug and/or alcohol abuse.
Patients who cannot give informed consent.