RecruitingNCT06687291

Cognitive Impact Associated With Surgery For Gastric Or Esophageal Cancer

Sponsor

Karolinska Institutet

Enrollment

130 participants

Start Date

Feb 13, 2025

Study Type

OBSERVATIONAL

Conditions

Sarcopenia Quality of Life (QOL)Chemotherapy Depression Gastroesophageal Cancer (GC)Frailty Malnutrition Postoperative Delirium (POD)Chemobrain

Summary

The primary objective of this observational study is to investigate the incidence of Post Operative Delirium (POD) after gastroesophageal cancer surgery. Secondary objectives are to investigate the relationship between POD, preoperative depression, frailty, quality of life, malnutrition and sarcopenia. Participants identified with POD will be asked (at the routine follow-up meeting after surgery) to participate in an qualitative interview, in order to understand the participant's experience of postoperative delirium. The main objective aims to answer: What is the incidence of POD after gastroesophageal cancer surgery.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study investigates how surgery for stomach (gastric) or esophageal cancer affects thinking, memory, and cognitive function before and after the operation, to better understand and potentially reduce post-surgical cognitive side effects. **You may be eligible if...** - You have been diagnosed with esophageal or gastric cancer - You are scheduled for surgery (with or without prior chemotherapy) - You are 18 years or older - You are able to provide informed consent **You may NOT be eligible if...** - You already have cognitive decline or dementia before surgery - You are not a candidate for surgery (e.g., due to metastatic disease) - You have severe hearing or vision problems that prevent communication - You have ongoing drug or alcohol abuse - You cannot give informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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