An Individualized Online Home-Based Exercise Program for Improving Symptoms in Gynecologic Cancer Survivors
Feasibility and Acceptability of an Individualized Online Home-Based Exercise Program on Psychoneurological Symptoms in Gynecologic Cancer Survivors: A Pilot Study
Emory University
40 participants
Sep 1, 2025
INTERVENTIONAL
Conditions
Summary
This clinical trial tests an individualized online home-based exercise program in gynecologic cancer survivors and its impact on gut microbiome (the bacteria and microorganisms that live in the digestive system) and symptoms such as pain, fatigue, sleep disturbance, depression, and cognitive impairment. These symptoms can significantly reduce the quality of life (QoL) and survival rate in this cancer population. Thus, promoting physical activity among cancer survivors may help mitigate these severe symptoms. Using online platforms such as Zoom can help participants access an individualized exercise program that meets their specific needs to engage in physical activity and decrease their symptom burden. Home-based exercise, by providing self-chosen time and location and low costs, can address some barriers to physical activity for cancer survivors. An individualized online home-based exercise program may be feasible, and may improve symptoms and quality of life in gynecologic cancer survivors.
Eligibility
Inclusion Criteria5
- Women aged ≥ 18 years old
- Previously diagnosed with gynecologic cancer (e.g., uterine, ovarian, cervical)
- Completed cancer treatment (chemotherapy or chemoradiation)
- Able to read and speak English
- Do not meet recommended exercise levels as defined by The American College of Sports Medicine
Exclusion Criteria4
- History of metastatic or other primary cancer
- Serious mental health conditions (e.g., bipolar disorder, schizophrenia, major depression)
- Certain chronic diseases (e.g., muscular-skeletal diseases that limit mobility, autoimmune diseases, uncontrolled diabetes, hypertension, renal disease (creatinine > 2.5 mg/dL)
- Unable to read/speak English
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Interventions
Participate in an individualized online home-based exercise intervention
Complete functional capacity assessment
Wear an activity tracker
Ancillary studies
Receive social support
Locations(4)
View Full Details on ClinicalTrials.gov
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NCT06709534