RecruitingNot ApplicableNCT06710353

The Effect of Preoperative Albumin Administration on Postoperative Acute Kidney Injury in Pediatric Patients With Hypoalbuminemia Undergoing Cardiac Surgery

The Effect of Preoperative Albumin Administration on Postoperative Acute Kidney Injury in Pediatric Patients With Hypoalbuminemia Undergoing Cardiac Surgery: A Prospective Randomized Clinical Trial

Sponsor

Seoul National University Hospital

Enrollment

190 participants

Start Date

Jan 9, 2025

Study Type

INTERVENTIONAL

Conditions

Acute Kidney Injury Pediatric Cardiac Surgery

Summary

The study aims to evaluate whether preoperative albumin supplementation in pediatric patients with hypoalbuminemia undergoing cardiac surgery can reduce inflammatory responses and prevent acute kidney injury (AKI) following cardiopulmonary bypass.

Eligibility

Max Age: 7 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Albumin solution and a drug called Crystalloid solutions for people with acute kidney injury and pediatric cardiac surgery. The study is currently recruiting participants at 1 location. People eligible for this study include up to age 7 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGAlbumin solution

A 20% albumin solution is administered over one hour starting from the induction of anesthesia, using the following formula: (4.0-preoperative serum albumin (g/dL))×plasma volume (kg×0.65-0.8 dL)

DRUGCrystalloid solutions

The same volume of crystalloid solution as the administered albumin is infused.

Locations(1)

Seoul National University Hospital

Seoul, Seoul, South Korea

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NCT06710353

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