Walking Program in Fatty Liver Children With Phenylketonuria

This study tests whether a supervised online walking program can reduce non-alcoholic fatty liver disease in children with phenylketonuria (PKU), a rare inherited metabolic disorder that affects protein processing and is associated with metabolic complications including fatty liver. PKU children in the study who also have fatty liver and are overweight will be randomly assigned to either an 8-week daily online-supervised walking program or a waitlist control group. Eligible participants are children with PKU who are obese and have non-alcoholic fatty liver, without cardiac, diabetic, neurological, respiratory, or renal conditions that would prevent safe exercise. Participation involves following the supervised walking plan daily for 8 weeks and being monitored for changes in liver health and metabolic markers. This summary was prepared using AI to help patients understand the study in plain language.