Non-alcoholic Fatty Liver Clinical Trials

2 recruiting

Frequently Asked Questions

Common questions about Non-alcoholic Fatty Liver clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 20 trials

Recruiting

Comorbidities Resolution After MGB Surgery and Change in Body Composition

HypertensionNon-Alcoholic Fatty Liver DiseaseSleep Apnea+5 more
All India Institute of Medical Sciences, Bhubaneswar35 enrolled1 locationNCT06015620
Recruiting

"Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".

Liver CancerNon-Alcoholic Fatty Liver DiseaseNon Alcoholic Steatohepatitis+4 more
Institut National de la Santé Et de la Recherche Médicale, France800 enrolled1 locationNCT04690972
Recruiting
Phase 4

Quantifying Hepatic Mitochondrial Fluxes in Humans

Non-Alcoholic Fatty Liver DiseaseType 2 DiabetesMitochondrial Metabolism Disorders
The University of Texas Health Science Center at San Antonio60 enrolled2 locationsNCT05305287
Recruiting
Not Applicable

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

Insulin Sensitivity/ResistanceObesityInsulin Resistance+16 more
Pichamol Jirapinyo, MD, MPH132 enrolled2 locationsNCT06138821
Recruiting

Single-cell Multiomics and Spatiotemporal Omics Analyze the Mechanism of Liver Degenerative Disease

Liver NeoplasmLiver FibrosisHBV Infection+1 more
Nanfang Hospital, Southern Medical University240 enrolled1 locationNCT07265544
Recruiting

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

Lung CancerCancer RiskCancer Predisposition Syndrome+28 more
Dana-Farber Cancer Institute5,000 enrolled1 locationNCT05463796
Recruiting

Cardiovascular Risk in Children With Chronic Conditions Study

Obesity and OverweightLymphomaLeukemia+22 more
Semmelweis University300 enrolled3 locationsNCT07086989
Recruiting

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM)

ObesityNon-Alcoholic Fatty Liver DiseaseHealthy+1 more
Bettina Mittendorfer60 enrolled1 locationNCT06571474
Recruiting
Early Phase 1

The Gut, Liver And Metabolome in Human Immunodeficiency Virus and Non Alcoholic Fatty Liver Disease

Non-Alcoholic Fatty Liver DiseaseHIVMetabolic-Associated Steatotic Liver Disease
Vanderbilt University Medical Center63 enrolled1 locationNCT06113003
Recruiting
Phase 2

Semaglutide Effects in Obese Youth With Prediabetes/New Onset Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease

Non-Alcoholic Fatty Liver DiseaseImpaired Glucose ToleranceType 2 Diabetes Mellitus+1 more
Yale University60 enrolled1 locationNCT05067621
Recruiting
Not Applicable

OneSTOP (One-Stop Telehealth Obesity Program) for Multidisciplinary Weight Management and Related Comorbidities

HypertensionTelemedicineDyslipidaemia+2 more
Changi General Hospital120 enrolled1 locationNCT06890169
Recruiting

CHronic Hepatopathies Associated with ALcohol Consumption and MetAbolic Syndrome

Hepatocellular CarcinomaNon-Alcoholic Fatty Liver DiseaseNon Alcoholic Steatohepatitis+2 more
Institut National de la Santé Et de la Recherche Médicale, France710 enrolled1 locationNCT05623150
Recruiting
Not Applicable

Change of Adipose Tissues and Triglyceride After Bariatric Surgery or Life-style Intervention

Diabetes MellitusInsulin ResistanceMetabolic Disease+4 more
Chinese University of Hong Kong80 enrolled1 locationNCT03875625
Recruiting

Increased Risk of Non-alcoholic Fatty Liver Disease in Low Birth Weight Individuals

Non-Alcoholic Fatty Liver DiseaseLow Birth Weight
Steno Diabetes Center Copenhagen300 enrolled1 locationNCT05890365
Recruiting
Phase 1

A Phase 1b Study of QX1206 in T2DM Patients With NAFLD

Type 2 Diabetes Mellitus (T2DM)Non-alcoholic Fatty Liver Disease NAFLD
1Globe Health Institute52 enrolled1 locationNCT06694935
Recruiting
Not Applicable

Effects of VLCKD in Metabolic Syndrome

ObesityMetabolic SyndromeNon-Alcoholic Fatty Liver Disease+1 more
Azienda Ospedaliero Universitaria Maggiore della Carita40 enrolled1 locationNCT05275608
Recruiting
Not Applicable

The Metabolic Impact of Intermittent Carbohydrate Restriction in Individuals With Type 2 Diabetes

Metabolic SyndromeNon-Alcoholic Fatty Liver DiseaseDiabetes Mellitus, Type 2+1 more
Hvidovre University Hospital14 enrolled1 locationNCT06144593
Recruiting
Not Applicable

A Prospective, Randomized, Open Label Trial of Two Doses of Oral Betaine

Non-Alcoholic Fatty Liver DiseaseNon Insulin Dependent DiabetesALT
Southern California Institute for Research and Education48 enrolled1 locationNCT03073343
Recruiting

Digitalized Surveillance Management for Liver Cancer Risk Population in Improving Eearly Diagnosis Efficancy in Chinese Population (dSEARCH)

Carcinoma, HepatocellularNon-Alcoholic Fatty Liver DiseaseCirrhosis, Liver+2 more
Ruijin Hospital20,000 enrolled1 locationNCT05870969
Recruiting

European Paediatric Non-Alcoholic Fatty Liver Disease Registry (EU-PNAFLD)

Non-Alcoholic Fatty Liver DiseaseNon Alcoholic SteatohepatitisNon-alcoholic Fatty Liver
Cambridge University Hospitals NHS Foundation Trust2,000 enrolled3 locationsNCT04190849