RecruitingNot ApplicableNCT06725550

Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0

Integrative Medicine in Pain Management in Sickle Cell Disease: Assessing the Clinical Efficacy and Neurobiological Impact With Acupuncture, 2.0

Sponsor

Indiana University

Enrollment

120 participants

Start Date

Aug 25, 2025

Study Type

INTERVENTIONAL

Conditions

Pain Magnetic Resonance Imaging Sickle Cell Disease Acupuncture Electroencephalography Quantitative Sensory Testing Circulating Biomarkers Functional Near-infrared Spectroscopy

Summary

The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupuncture analgesia in patients with sickle cell disease.

Eligibility

Min Age: 14 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called laser acupuncture and a medical device called needling acupuncture for people with acupuncture, circulating biomarkers, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 14 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DEVICEneedling acupuncture

Acupuncture treatment will both main and supplementary acupoints. Main points include GB30; ST36; LI11- LI4, GB34-SP6; LR3, SP10, DU24, DU20, Yin Tang, Ear Shen Men which are chosen based on the unique clinical features of sickle pain. The remaining individualized acupoints will be selected and manipulated with manual acupuncture with appropriate needling techniques based on the individual "Syndrome" ("reinforce" or "reduce" or "Non reinforce or reduce") that is determined by TCM diagnosis.

DEVICElaser acupuncture

Laser acupuncture device VitaLaser 650 (Lhasa OMS, Weymouth, MA or similar) will be positioned 1-2cm over all of the same acupoints used in verum acupuncture treatment above. No palpation is administered prior to positioning the device and there is no physical contact between device and skin.