RecruitingEarly Phase 1NCT06734572

18F-FAPIBiotin PET/CT: Dosimetry and Biodistribution Study

18F-FAPIBiotin PET/CT: Dosimetry and Biodistribution Study in Patients With Various Cancers


Sponsor

First Affiliated Hospital of Fujian Medical University

Enrollment

5 participants

Start Date

Jun 25, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

As a new dual targeting PET radiotracer, 18F-FAPI-Biotin is promising as an excellent imaging agent applicable to various cancers. In this study, we observed the safety, biodistribution and radiation dosimetry of 18F-FAPI-Biotin in patients with various types of cancer and compared them with the results of 18F-FAPI or 18F-FDG imaging to evaluate the dosimetric characteristics and diagnostic efficacy of 18F-FAPI.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria1

  • Various solid tumors with available histopathological findings • Signed informed consent

Exclusion Criteria1

  • pregnant or lactational women • who suffered from severe hepatic and renal insufficiency

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Interventions

DRUG18F-FAPIBiotin

The dose will be 148-296 MBq given intravenously.


Locations(1)

Department of Nuclear Medicine, First Affiliated Hospital of Fujian Medical University

Fuzhou, Fujian, China

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NCT06734572


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