RecruitingPhase 2NCT06740526

Trial of the Impact of Sibeprenlimab on Immunoglobulin A Nephropathy Kidney Tissue

A Phase 2b, Multicenter, Open-label, Single-arm Trial to Evaluate the Impact of Sibeprenlimab on Kidney Histopathology Through Repeat Kidney Biopsies in Adolescents and Adults With Immunoglobulin A Nephropathy


Sponsor

Otsuka Pharmaceutical Development & Commercialization, Inc.

Enrollment

25 participants

Start Date

Nov 19, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This is a phase 2b open-label trial to characterize histopathological biomarkers of disease in immunoglobulin A nephropathy (IgAN) and demonstrate potential changes in response to sibeprenlimab.


Eligibility

Min Age: 16 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Sibeprenlimab for people with iga nephropathy. The study is currently recruiting participants at 5 locations. People eligible for this study include aged 16 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSibeprenlimab

Sibeprelimab SC (Period 1) Sibeprelimab SC (Period 2)


Locations(5)

Clinical Research Site 330

Denver, Colorado, United States

Clinical Research Site 369

Boston, Massachusetts, United States

Clinical Research Site 374

Dakota Dunes, South Dakota, United States

Clinical Research Site 324

Houston, Texas, United States

Clinical Research Site 305

Scarborough Village, Ontario, Canada

View Full Details on ClinicalTrials.gov

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NCT06740526


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