NWRD09 for HPV-16 Positive and HPV-16 Related Intraepithelial Neoplasia and Cervical Cancer Patients.

This study tests a therapeutic vaccine called NWRD09 in women with HPV-16 related cervical abnormalities or cervical cancer. HPV-16 is the most common strain of human papillomavirus linked to cervical cancer. The vaccine aims to train the immune system to attack HPV-16-infected cells. **You may be eligible if...** - You are a woman between 18 and 60 years old - You have tested positive for HPV-16 - You have high-grade cervical cell changes (HSIL) or early-stage cervical cancer - Your colposcopy exam showed the abnormal area is fully visible (satisfactory colposcopy) **You may NOT be eligible if...** - You are outside the age range of 18–60 - Your HPV test is negative for HPV-16 - The abnormal cervical area cannot be fully visualized during colposcopy - You have health conditions that would make participation unsafe Talk to your doctor to see if this trial is right for you.