RecruitingNot ApplicableNCT06756594

Efficacy of Dexmedetomidine-Propofol Versus Ketamine-Propofol for Sedation

Efficacy of Dexmedetomidine-Propofol Versus Ketamine-Propofol for Sedation During Gastrointestinal Endoscopy


Sponsor

Sohag University

Enrollment

100 participants

Start Date

Nov 12, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to compare efficacy of sedation between Dexmedetomidine-Propofol and Ketamine-Propofol combinations in the upper or lower gastrointestinal system endoscopy. We compare between 2 combinations as regard hemodynamic stability, post operative side effects as occurrence of delirium, nausea, vomiting, headache, hallucination or agitation.


Eligibility

Min Age: 18 YearsMax Age: 60 Years

Inclusion Criteria3

  • American Society of Anesthesiologists physical status I to II.
  • Age between 18 and 60 years.
  • Both sexes.

Exclusion Criteria2

  • Having severe heart, lung, liver disease, kidney failure, or bleeding disorder.
  • Patients having fever, hypothermia or infection, electrolyte disorders, such as hypokalemia and hypocalcaemia, acid-base disorder, allergy to drugs to be used.

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Interventions

DRUGDexmedetomidine-Propofol

efficacy of sedation with Dexmedetomidine-Propofol combination in the upper or lower gastrointestinal system endoscopy.

DRUGKetamine-Propofol

efficacy of sedation with Ketamine-Propofol combination in the upper or lower gastrointestinal system endoscopy.


Locations(1)

Sohag University Hospital

Sohag, Egypt

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NCT06756594


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