Propofol Clinical Trials

9 recruiting

Frequently Asked Questions

Common questions about Propofol clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 118 of 18 trials

Recruiting

Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients

OxygenationAirway ManagementCritically Ill+3 more
Zeliha Alicikus4 enrolled1 locationNCT07222007
Recruiting
Phase 3

Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)

AnesthesiaAnesthesia ComplicationAnesthesia; Reaction+3 more
University of Texas Southwestern Medical Center200 enrolled1 locationNCT05358535
Recruiting

Minto and Eleveld Remifentanil Target Controlled Infusion (TCI) Models: a Clinical Comparison

Anesthesia Brain MonitoringPropofolRemifentanil
University of Padova100 enrolled1 locationNCT07259291
Recruiting

A Comparative Study of Eleveld and Schnider Pharmacokinetic Models for Target-Controlled Infusion of Propofol in Sedation of Mechanically Ventilated ICU Patients

SedationIntensive Care Unit SedationTarget Controlled Infusion of Propofol
Hacettepe University84 enrolled1 locationNCT07239687
Recruiting
Not Applicable

Robotic-assisted Bronchoscopy Under Moderate Sedation With Propofol

BronchoscopyPropofolLung Lesions+2 more
University of Zurich30 enrolled1 locationNCT07006311
Recruiting
Not Applicable

Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension

Brain IschemiaKetamineMagnesium Sulfate+6 more
University General Hospital of Patras150 enrolled1 locationNCT07181564
Recruiting
Not Applicable

Sevoflurane With or Without Intravenous Lidocaine Infusion Versus Propofol Anesthesia on Intracranial Pressure and Cerebral Oxygenation During Laparoscopic Hysterectomy

Cerebral OxygenationPropofolSevoflurane+2 more
Tanta University90 enrolled1 locationNCT07062367
Recruiting
Not Applicable

Safety of Etomidate-propofol Mixture vs. Propofol for Total Intravenous Anesthesia in Elderly Patients Undergoing Abdominal Surgery

HypertensionEtomidate Combined With Propofol
Tongji Hospital166 enrolled1 locationNCT07019246
Recruiting
Not Applicable

Remimazolam Besylate in Sedation of Postcardioperative Patients

Mechanical VentilationRemimazolamSedation+3 more
First Affiliated Hospital of Zhejiang University120 enrolled1 locationNCT06716840
Recruiting

The Effects of Anesthetics on Brain Network Connectivity in Patients With Supratentorial Glioma

DexmedetomidinePostoperative DeliriumPropofol+1 more
Beijing Tiantan Hospital120 enrolled1 locationNCT06138340
Recruiting
Not Applicable

Efficacy of Dexmedetomidine-Propofol Versus Ketamine-Propofol for Sedation

Propofol
Sohag University100 enrolled1 locationNCT06756594
Recruiting
Not Applicable

Hemodynamic Effects of a High Dose Versus Low Dose Propofol During Induction of Anesthesia.

Hemodynamic Effects of Propofol
Ain Shams University70 enrolled1 locationNCT06651749
Recruiting
Phase 4

Evaluation of Propofol Dosing Based on Total Body Weight Using Closes-loop Anaesthesia Delivery System

AnesthesiaObesity, MorbidPropofol
Sir Ganga Ram Hospital46 enrolled1 locationNCT05305313
Recruiting
Not Applicable

Additive Effects of Clonidine Used in Propofol Sedation in Colonoscopy

ColonoscopySedationPropofol+1 more
Tanta University62 enrolled1 locationNCT06507410
Recruiting

The efficacy of ondansetron as an adjunct to lidocaine compared with lidocaine pretreatment in reducing pain on propofol injection: A randomized controlled trial

Pain on propofol injection
King Chulalongkorn Memorial Hospital260 enrolled1 locationACTRN12624000248561
Recruiting
Phase 4

A comparison of dexmedetomidine combined with propofol for conscious sedation during endoscopic retrograde cholangiopancreatography(ERCP)

Although target controlled infusion(TCI) systems decrease the risk of respiratory during sedation with propofol, the risk persists.
Dr Qianbo Chen60 enrolledACTRN12612000964819
Recruiting

Analgesic, Sedative and Antibiotic Pharmacokinetics during Extracorporeal Membrane Oxygenation: Understanding altered pharmacokinetics to improve patient outcomes.

Alterations to the pharmacokinetics of broad spectrum antibiotics (ceftriaxone, cefepime, meropenem, gentamicin, ciprofloxacin, ticarcillin-clavulanate, piperacillin-tazobactum, vancomycin, linezolid, caspofungin, fluconazole, voriconazole, oseltamivir/oseltamivir carboxylate) in critically ill patients receiving ECMO.Alterations to the pharmacokinetics of sedative and analgesic drugs and their metabolites (morphine - morphine 3 glucorunide, morphine 6 glucuronide, midazolam - 1 and 4 hydroxy midazolam, fentanyl - norfentanyl, dexmedetiomedine, propofol, thiopentone) in critically ill patients receiving ECMO.
Critical Care Research Group160 enrolled4 locationsACTRN12612000559819
Recruiting
Phase 4

Effect of Propofol on Ability to Drive

Driving impairment by Propofol
Monash Medical Centre20 enrolled1 locationACTRN12611000385943