RecruitingNCT06760923

Urinary Proteomic Assessment of Ovarian Malignancy and Disease Progression


Sponsor

Xiangya Hospital of Central South University

Enrollment

240 participants

Start Date

Jan 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to determine the urinary proteomic characteristics in women with and without ovarian cancer. The main questions it aims to answer are: 1. What is the difference in urinary protein composition between patients with ovarian cancer and those without it? 2. Can these differences in urinary protein composition aid in the diagnosis of ovarian cancer? 3. Are urinary protein markers associated with tumor burden in urine samples from patients with ovarian cancer? 4. Can urinary protein markers be used for disease surveillance in ovarian cancer patients?


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is collecting urine samples from women having gynecological surgery to see if proteins in urine can help detect ovarian cancer or track how it progresses. It is a research study, not a treatment trial. **You may be eligible if...** - You are a woman aged 18 or older scheduled for gynecological surgery - You have been diagnosed with a pelvic mass, malignant ascites (fluid that may suggest ovarian cancer), or a condition like ovarian cyst, uterine fibroids, or adenomyosis - You are willing to provide urine samples **You may NOT be eligible if...** - You have a prior history of any cancer - You have chronic kidney disease or kidney failure - You are already receiving treatment for your current condition - Your diagnosis is unclear from pathology Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Xiangya Hosipital of Central South University

Changsha, Hunan, China

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NCT06760923


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