The HIEnome Study: Genome Sequencing for Perinatal HIE
Baylor College of Medicine
25 participants
May 15, 2025
INTERVENTIONAL
Conditions
Summary
Perinatal hypoxic-ischemic encephalopathy is a rare severe condition in which neonates present with encephalopathy and a clinical history suggestive of prenatal or perinatal hypoxic-ischemic injury. Emerging evidence suggests that genetic conditions are frequently identified in cases of perinatal HIE; however, it is unclear which neonates with this diagnosis warrant genetic testing. This study will offer clinical genome sequencing to neonates with HIE who are undergoing total body cooling (therapeutic hypothermia) and their parents.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Neonates enrolled in this study will undergo genome sequencing with parental controls as applicable.
Locations(2)
View Full Details on ClinicalTrials.gov
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NCT06762795