RecruitingNCT06775106
Exhaled Breath: A Novel Technique for Rapid Diagnosis of Respiratory Diseases and Infections
Sponsor
Oregon Health and Science University
Enrollment
100 participants
Start Date
Nov 30, 2024
Study Type
OBSERVATIONAL
Conditions
Summary
This study aims to use mass spectrometry techniques to analyze exhaled patient breath in non-COVID ICU-admitted patients requiring ventilation for a rapid and accurate early detection of pulmonary diseases and inflammatory markers.
Eligibility
Min Age: 18 YearsMax Age: 120 Years
Inclusion Criteria1
- Non-COVID-19 adult consented patients (>18yo) on ventilatory support in the ICU at OHSU
Exclusion Criteria2
- Patients with "severe respiratory distress" as defined by arterial pO2 of <60 mmHg on maximal FiO2 \& optimal ventilator settings
- Patient with severe hemodynamic instability as defined by (a) receiving IV infusion of 2 or more pressors or inotropic medications (Levophed, vasopressin, phenylephrine, or epinephrine) \& (b) MAP of <60 mmHg or SB <80 mmHg
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Interventions
OTHERThere is no intervention in this observational study
No direct intervention will be done to patients eligible for the study. There will be a shunt placed to divert 5-15% of exhaled breath into a collection tube. This will not affect the patient's existing standard medical care.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06775106
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