Comparison of Remimazolam and Propofol in Endoscopic Examinations and Treatments

This study is comparing two sedation medications — remimazolam and propofol — used to keep patients comfortable and relaxed during upper digestive tract (upper GI) endoscopy procedures. Researchers want to find out which medication is safer, works better, and causes fewer side effects during these routine procedures. **You may be eligible if...** - You are between 20 and 80 years old - You are scheduled for an upper GI endoscopy (such as a gastroscopy) - Your overall health is rated as acceptable for sedation by an anesthesiologist (ASA class I–III) **You may NOT be eligible if...** - You are allergic to propofol, remimazolam, or opioid pain medications - It is an emergency procedure - You are pregnant - You have a history of malignant hyperthermia (a rare reaction to anesthesia) - You have liver or kidney problems - You have throat or airway problems that complicate sedation Talk to your doctor to see if this trial is right for you.