RecruitingNCT06780150

A Study to Investigate Effects of Ocrelizumab Treatment on Neurofilament Light Chain (NfL) Levels and Participant Satisfaction in Participants With Multiple Sclerosis (MS)

SurfSubQ - A Prospective Longitudinal Multicenter Observational Study to Investigate Neurofilament Light Chain Levels and Patient Satisfaction After Subcutaneous Ocrelizumab Administration in Persons With Multiple Sclerosis

Sponsor

Hoffmann-La Roche

Enrollment

842 participants

Start Date

Sep 26, 2024

Study Type

OBSERVATIONAL

Conditions

Multiple Sclerosis

Summary

The main purpose of the study is to evaluate participant satisfaction after administration of ocrelizumab subcutaneous (SC) after 12 months using the therapy administration satisfaction questionnaire subcutaneous (TASQ-SC).

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is tracking patients with multiple sclerosis (MS) who are starting or switching to subcutaneous (under the skin) ocrelizumab injections, to measure changes in a brain injury protein in the blood called neurofilament light chain (NfL) and to gather information on how satisfied patients are with this form of treatment. **You may be eligible if...** - You have been diagnosed with multiple sclerosis (relapsing MS or primary progressive MS) - You are starting your first treatment with subcutaneous ocrelizumab according to the prescribing information - You have not previously been treated with rituximab or ublituximab **You may NOT be eligible if...** - You are already participating in another interventional MS drug study - You have previously participated in the CONFIDENCE or MoOzaRt non-interventional studies at the same site - You have severe psychiatric illness - You are pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGOcrelizumab

Ocrelizumab will be administered as SC injection as per discretion of the treating physician in accordance with local clinical practice and local labeling.

Locations(84)

Uniklinik RWTH Aachen

Aachen, Germany

Gesundheitszentrum St. Marien GmbH

Amberg, Germany

Neuropraxis im Stadtpalais Dres. Ulzheimer/Herröder/Wessig GbR

Aschaffenburg, Germany

Neurologie Bad Soden

Bad Soden, Germany

Neurologische Praxis - Kallmann Neurologie - mszb

Bamberg, Germany

Neurologisches Facharztzentrum Berlin am Sankt Gertrauden-Krankenhaus

Berlin, Germany

NEUROZENTRUM tempelhof.berlin

Berlin, Germany

Praxis Dr. Said Masri

Berlin, Germany

Jüdisches Krankenhaus Berlin

Berlin, Germany

NeuroZentrum Zehlendorf Dr. Ringel und Dr. Scherer

Berlin, Germany

Neurologisches Zentrum für Bewegungsstörungen und Diagnostik

Berlin, Germany

St. Josef-Hospital

Bochum, Germany

Dres. Lippert/Kausch

Bogen, Germany

Krankenhaus Buchholz Abt. Neurologie

Buchholz, Germany

Allgemeines Krankenhaus Celle / Klinik für Neurologie

Celle, Germany

Neuropraxis Celle: Praxis für Neurologie & Psychatrie

Celle, Germany

Praxisgemeinschaft Dres. Sylke Domke und Vasil Gjaurov

Chemnitz, Germany

NeuroMed Campus Neurologische Gemeinschaftspraxis am St. Elisabeth Krankenhaus

Cologne, Germany

Gemeinschaftspraxis Dr. med. Josef Leclaire und Dr. med. Thomas Rotermund

Dortmund, Germany

Gemeinschaftspraxis für Neurologie

Düsseldorf, Germany

Universitätsklinikum Düsseldorf

Düsseldorf, Germany

Nervenarztpraxis Gerresheim

Düsseldorf, Germany

Gemeinschaftspraxis für Neurologie und Psychiatrie, Psychotherapie

Eltville, Germany

NeuroCentrum Odenwald

Erbach/Odenwald, Germany

Universitätsklinikum Erlangen, Neurologische Klinik

Erlangen, Germany

Zentrum für ambulante Neurologie / Praxis Knorn Landefeld Friedrich

Essen, Germany

Praxis Nervenstark

Essen, Germany

Praxis für Neurologie, Nervenheilkunde & Neurochirurgie

Forchheim, Germany

Varisano Klinikum Frankfurt Höchst GmbH

Frankfurt, Germany

Universitätsklinikum Freiburg, Klinik für Neurologie und Neurophysiologie

Freiburg im Breisgau, Germany

Praxis im Bahnhof

Füssen, Germany

Universitätsklinikum Gießen und Marburg GmbH

Giessen, Germany

Neurologie & Psychiatrie Gladenbach - MS-Zentrum

Gladenbach, Germany

MVZ Bezirkskliniken Schwaben, Standort Günzburg

Günzburg, Germany

Krankenhaus Martha-Maria Halle-Doelau

Halle, Germany

Universiätsklinikum Hamburg-Eppendorf

Hamburg, Germany

Neurologische Praxis Eppendorf

Hamburg, Germany

Neurologische Praxis

Hanover, Germany

Oberhavel Kliniken GmbH, Klinik Hennigsdorf, Neurologie

Hennigsdorf, Germany

Praxis Dr. Hospely

Herford, Germany

Haus- und Facharztzentrum Laucherttal / Alb

Hettingen, Germany

Klinikum Ibbenbüren gmbH

Ibbenbueren, Germany

Augustahospital Anholt;Neurologie

Isselburg, Germany

Universitätsklinikum Jena, Klinik für Neurologie

Jena, Germany

Arztpraxis Dr. med. Torsten Sühnel

Leipzig, Germany

Neurologische Praxis Dr. Ehrlich

Leipzig, Germany

Neurologie im Ulrichshaus Magdeburg

Magdeburg, Germany

Universitätsklinikum Magdeburg

Magdeburg, Germany

Neuroplus Dres. Lennart Thilmann/ Patrick Thilmann

Mannheim, Germany

Universitätsklinikum Mannheim

Mannheim, Germany

Universitätsklinikum Giessen und Marburg

Marburg, Germany

Praxis Dr. Leussink

Meerbusch, Germany

Neurologie am Preußenmuseum

Minden, Germany

Neurologie München Nord

München, Germany

Praxis für Neurologie und Psychiatrie am Prinzregentenplatz

München, Germany

Neurologisch-psychiatrische Praxis im A4

Neu-Ulm, Germany

Praxis Dr. med. Bergmann

Neuburg am Inn, Germany

Gemeinschaftspraxis Uhlig und Windsheimer

Nuremberg, Germany

Neurologie Nürnberg-Eibach

Nuremberg, Germany

Neurologie an der Hase

Osnabrück, Germany

Dres. Beckmann / Schlüter

Öhringen, Germany

Facharztpraxis für Neurologie und Psychiatrie Dres Mattes/Stockert

Pforzheim, Germany

Neurologisches Studienzentrum Artland

Quakenbrück, Germany

Gemeinschaftspraxis für Neurologie

Regensburg, Germany

Praxis Dr. Stienker-Fisse

Remscheid, Germany

ZNS Südpfalz

Rülzheim, Germany

Neurologische Praxis Dr. Wagner

Schwetzingen, Germany

Gemeinschaftspraxis für Neurologie, Psychiatrie und Psychotherapie

Siegen, Germany

Praxis für Neurologie und Psychiatrie

Siegen, Germany

EMSA - Zentrum für Neurologie?/?Psychiatrie?/?Neuroradiologie

Singen, Germany

Praxis Dr. med. Max Deist und Michael Ernst ?Sinsheim

Sinsheim, Germany

Gemeinschaftspraxis Dr. Wolfram von Pannwitz, MBA & Dr. med. Marie Perle Brinckmann

Steglitz, Germany

Praxis Dr. med. Andreas Kowalik, Arzt für Neurologie und Psychiatrie

Stuttgart, Germany

Neuropraxis Sotiriadis

Stuttgart, Germany

Neurozentrum Stuttgart Mitte Sophienstraße

Stuttgart, Germany

Sauerlandklinik Hachen

Sundern, Germany

Universitätsklinikum Tübingen, Zentrum für Neurologie

Tübingen, Germany

Nervenfachaerztliche Gemeinschaftspraxis Ulm

Ulm, Germany

Neuropraxis München Süd

Unterhaching, Germany

Praxis für Neurologie, Psychiatrie und Epileptologie

Weil der Stadt, Germany

Praxis Dr. Michaela Krause

Wolfratshausen, Germany

Heinrich-Braun-Krankenhaus Städtisches Klinikum

Zwickau, Germany

Inselspital-Universitaetsspital Bern

Bern, Switzerland

Bellevue Medical Grop AG

Zurich, Switzerland

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NCT06780150

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