RecruitingNot ApplicableNCT06782178

TMJ Arthroscopy Compared to Arthrocentesis in Disc Displacement Without Reduction

Temporomandibular Joint Arthroscopic Lysis and Lavage Compared to Arthrocentesis in Disc Displacement Without Reduction: a Randomised, Double-blind, Controlled Trial


Sponsor

Karolinska Institutet

Enrollment

100 participants

Start Date

Apr 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to compare the intervention arthroscopic lysis and lavage to the intervention arthrocentesis in treating disabling and painful temporomandibular joint disc displacement without reduction. The main questions it aims to answer are: * Which surgical method that best improves mouth opening capacity, TMJ pain, and TMJ disability? * If any pre- or peri-operative variable/-s could be identified as a predictor for surgical outcome? Researchers will compare arthroscopic lysis and lavage to arthrocentesis to see if arthroscopic lysis and lavage works better to treat temporomandibular joint disc displacement. Participants will: * Have one of the two interventions under general anesthesia, not knowing which intervention. * Visit an external clinic for regular checkups at 1, 3, 6, 12, and 24 months after surgery. * Answer three different quality of life surveys at the checkups.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Uni- or bilateral DDwoR affecting the patients mouth opening capacity to a range of ≤ 35 mm, verified with clinical and magnetic resonance imaging (MRI) findings.
  • TMJ pain ≥ 3 (NRS)
  • TMJ disability ≥ 3 (NRS)
  • Age ≥ 18 years

Exclusion Criteria4

  • Prior open TMJ surgery
  • Patient diagnosed with rheumatologic joint disease.
  • ASA (American Society of Anaesthesiologists) \> 3
  • Patient unable to verify informed consent.

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Interventions

PROCEDUREArthroscopic lysis and lavage

Arthroscopic lysis and lavage refers to an arthroscopic procedure where the temporomandibular joint is rinsed with saline solution and where the joint capsule is distended and where adhesions are lysated bluntly.

PROCEDUREArthrocentesis/Saline

Arthrocentesis refers to a blind irrigation of the temproromandibular joint with saline solution


Locations(1)

Karolinska Institutet

Huddinge, Sweden

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NCT06782178


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