RecruitingPhase 4NCT06784986

Impact of Using the Airseal System with Ultra-low Pneumoperitoneum in Patients Undergoing Robot-assisted Radical Prostatectomy: a Prospective, Comparative, Randomized Clinical Study.


Sponsor

Brazilian Institute of Robotic Surgery

Enrollment

200 participants

Start Date

Feb 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The AirSeal platform has been evaluated in urological surgeries, mainly in cases of malignant diseases 5,6. However, there is still a lack of data demonstrating the possible benefits of its use, which justifies the conduct of this research in order to aggregate such knowledge. Therefore, the objective of this prospective pilot study is to compare and evaluate the role of low-pressure pneumoperitoneum with the AirSeal system in patients with prostate cancer undergoing robot-assisted prostatectomy with those undergoing the procedure with the conventional insufflation system. We seek to provide more data on the use of AirSeal, which is associated with shorter operative times, shorter hospital stays and a lower probability of complications. In addition, we aim to ratify the effectiveness and cost-benefit of using the AirSeal system.


Eligibility

Sex: MALEMin Age: 18 YearsMax Age: 65 Years

Inclusion Criteria1

  • Patients with prostate cancer who will undergo robotic prostatectomy;

Exclusion Criteria4

  • Patients over 65 and under 18 years of age;
  • Patients allergic to NSAIDs and/or Morphine and/or Tramadol;
  • Patients with chronic renal failure;
  • Patients with recurrence, metastasis and other existing neoplasms.

Interventions

DEVICEThe Conventional Insufflation System

The Conventional Insufflation System employs standard CO2 insufflation techniques for maintaining intra-abdominal pressure during laparoscopic and robotic surgeries. It serves as the base for comparison with the AirSeal® System.

DEVICEAirSeal® System

The AirSeal® System consists of an insufflation, filtration, and recirculation system (AirSeal® IFS), a triple-lumen filtered tube set, and a valve-free trocar (AirSeal® Access Port). This innovative system allows peritoneal access and pneumoperitoneum maintenance without a mechanical seal, reducing CO2 usage and associated complications.


Locations(2)

Instituto Brasileiro de Cirurgia Robotica

Salvador, Estado de Bahia, Brazil

Hospital Mater Dei Salvador

Salvador, Estado de Bahia, Brazil

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NCT06784986


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