Prostate Carcinoma Clinical Trials

115 recruitingLast updated: June 17, 2026

There are 115 actively recruiting prostate carcinoma clinical trials across 16 countries. Studies span Phase 2, Not Applicable, Phase 1, Phase 3, Early Phase 1, Phase 4. Top locations include Los Angeles, California, United States, San Francisco, California, United States, Duarte, California, United States. Updated daily from ClinicalTrials.gov.


Prostate Carcinoma Trials at a Glance

115 actively recruiting trials for prostate carcinoma are listed on ClinicalTrialsFinder across 6 cities in 16 countries. The largest study group is Phase 2 with 40 trials, with the heaviest enrollment activity in Los Angeles, San Francisco, and Duarte. Lead sponsors running prostate carcinoma studies include Mayo Clinic, City of Hope Medical Center, and Jonsson Comprehensive Cancer Center.

Browse prostate carcinoma trials by phase

Treatments under study

About Prostate Carcinoma Clinical Trials

Looking for clinical trials for Prostate Carcinoma? There are currently 41 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Prostate Carcinoma trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Prostate Carcinoma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 115 trials

Recruiting
Phase 3

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

Stage IVB Prostate Cancer AJCC v8Metastatic Prostate AdenocarcinomaMetastatic Castration-Resistant Prostate Carcinoma
Alliance for Clinical Trials in Oncology1,524 enrolled98 locationsNCT07200830
Recruiting
Phase 1

Image-Guided Biopsies to Identify Mechanisms of Resistance in Patients With Metastatic Castration Resistant Prostate Cancer Treated With 177Lu-PSMA Radioligand Therapy

Castration-Resistant Prostate CarcinomaMetastatic Prostate CarcinomaStage IVB Prostate Cancer AJCC v8+2 more
Jonsson Comprehensive Cancer Center30 enrolled1 locationNCT05398302
Recruiting
Not Applicable

The Vanguard Study: Testing a New Way to Screen for Cancer

Breast CarcinomaOvarian CarcinomaBladder Carcinoma+8 more
National Cancer Institute (NCI)24,000 enrolled37 locationsNCT06995898
Recruiting
Phase 1Phase 2

Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive to Hormonal Therapy

Stage IVB Prostate Cancer AJCC v8Metastatic Malignant Neoplasm in the BoneMetastatic Castration-Resistant Prostate Carcinoma+1 more
National Cancer Institute (NCI)90 enrolled32 locationsNCT04071236
Recruiting
Phase 1

Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer

Castration-Resistant Prostate CarcinomaMetastatic Prostate CarcinomaStage IVB Prostate Cancer AJCC v8
Roswell Park Cancer Institute14 enrolled1 locationNCT06305598
Recruiting
Not Applicable

Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases

Malignant Brain NeoplasmMalignant Solid NeoplasmProstate Carcinoma+2 more
Mayo Clinic147 enrolled1 locationNCT06788886
Recruiting

Targeted Early Detection Program in Men at High Genetic Risk for Prostate Cancer

Prostate Carcinoma
University of Michigan Rogel Cancer Center200 enrolled1 locationNCT07645391
Recruiting
Phase 2

Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate CarcinomaStage IV Prostate Cancer AJCC v8Stage IVB Prostate Cancer AJCC v8+2 more
University of Utah33 enrolled1 locationNCT05168618
Recruiting
Early Phase 1

Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients

Metastatic Prostate CarcinomaStage IV Prostate Cancer AJCC v8Localized Prostate Carcinoma+1 more
Mayo Clinic220 enrolled2 locationsNCT05045066
Recruiting
Not Applicable

Two-fraction HDR Monotherapy for Localized Prostate Cancer

Prostate AdenocarcinomaLocalized Prostate Carcinoma
University of California, San Francisco17 enrolled1 locationNCT05665738
Recruiting
Phase 2

PSMA-Guided Ablation of the Prostate

Prostate CancerLocalized Prostate Carcinoma
University of Alberta138 enrolled4 locationsNCT06003556
Recruiting
Phase 2

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

Castration-Resistant Prostate CarcinomaStage IVB Prostate Cancer AJCC v8
Alliance for Clinical Trials in Oncology474 enrolled107 locationsNCT06632977
Recruiting
Phase 3

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

Stage IVB Prostate Cancer AJCC v8Metastatic Prostate AdenocarcinomaCastration-Sensitive Prostate Carcinoma
Alliance for Clinical Trials in Oncology1,260 enrolled194 locationsNCT06931340
Recruiting
Not Applicable

Golf Recreational Exercise for Enhanced Survivorship in Prostate Cancer Survivors

Locally Advanced Prostate CarcinomaStage III Prostate Cancer AJCC v8Localized Prostate Carcinoma+2 more
University of Southern California20 enrolled2 locationsNCT06500169
Recruiting

Integrating Quantitative MRI and Artificial Intelligence to Improve Prostate Cancer Classification

Prostate Carcinoma
Jonsson Comprehensive Cancer Center275 enrolled1 locationNCT04765150
Recruiting
Not Applicable

Oral Cryotherapy to Decrease Taste Changes in Prostate Cancer Patients Receiving Taxane Chemotherapy

Prostate Carcinoma
City of Hope Medical Center60 enrolled1 locationNCT07218718
Recruiting
Phase 2

Magnetic Resonance Imaging (MRI) With Hyperpolarized Pyruvate (13C) as Diagnostic Tool in Advanced Prostate Cancer

Prostate CancerAdvanced Prostate Carcinoma
Ivan de Kouchkovsky, MD75 enrolled1 locationNCT04346225
Recruiting
Phase 2

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

Breast CarcinomaUrothelial CarcinomaOvarian Carcinoma+26 more
Mayo Clinic27 enrolled1 locationNCT07285044
Recruiting
Phase 3

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

Metastatic Prostate CarcinomaStage IVB Prostate Cancer AJCC v8Biochemically Recurrent Prostate Carcinoma+1 more
ECOG-ACRIN Cancer Research Group804 enrolled342 locationsNCT04423211
Recruiting
Phase 2

Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer

Prostate CarcinomaStage III Prostate Cancer AJCC v8Stage IVA Prostate Cancer AJCC v8+4 more
M.D. Anderson Cancer Center200 enrolled1 locationNCT04947254