Development of Organoids From Primary Colorectal Tumors and Synchronous Liver Metastases

This study is collecting tumor tissue samples from patients with colorectal cancer that has spread to the liver, in order to grow miniature versions of their tumors in a lab (called organoids). These lab-grown tumor models help researchers understand why some treatments work for some patients but not others. **You may be eligible if...** - You are over 18 years old - You have been diagnosed with colorectal cancer (colon or rectal cancer) that has spread to the liver - You are scheduled to have surgery for your colorectal cancer and liver metastasis - You are willing and able to sign an informed consent form **You may NOT be eligible if...** - You do not meet the standard surgical criteria for the procedure (the same rules that apply to the surgery also apply to this study) Talk to your doctor to see if this trial is right for you.