RecruitingNCT06790160

Study of Patients Being Treated With Anti-obesity Medication

Observational Study of Patients Being Treated With Anti-obesity Medication

Sponsor

Texas Tech University

Enrollment

100 participants

Start Date

Jan 31, 2025

Study Type

OBSERVATIONAL

Conditions

Obesity and Overweight

Summary

The goal of this observational study is to learn about the real-world effects of selected obesity medications in adults undergoing medical weight management. The main outcomes of interest are changes in body composition, routine clinical markers, muscular performance, and nutritional intake over the course of treatment. Additionally, the influence of lifestyle factors on changes in these outcome variables will be examined. Participants beginning treatment with selected obesity medications will undergo periodic body composition and muscular performance testing, as well as complete online surveys about their nutritional intake and physical activity and exercise participation. Additionally, routinely collected clinical information will be evaluated.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This observational study tracks real-world changes in body composition, muscle strength, nutrition, and clinical markers in adults starting treatment with GLP-1 weight loss medications (semaglutide or tirzepatide) at a virtual health clinic. Unlike controlled trials, this study captures what actually happens in everyday medical settings, including how lifestyle factors like diet and exercise influence outcomes. Eligible participants must have a BMI of 30 or higher (or 27+ with a weight-related health condition), live near a DXA body composition scanning facility, and be starting one of the two specified medications. Participation involves body scans at baseline, 6 months, and 17 months; home handgrip strength testing; and online surveys about diet and exercise habits at multiple timepoints. This summary was prepared to help patients understand the study in plain language.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.