The Role of FAPI PET-CT in Diagnosing Endometriosis
Use of Fibroblast Activation Protein Inhibitor (FAPI) PET-CT Before Surgery in Patient with Endometriosis
Ziv Hospital
30 participants
Mar 1, 2025
INTERVENTIONAL
Conditions
Summary
Patients with suspected endometriosis scheduled for surgery will be identified. They will be asked to participate in a study evaluating the feasibility of FAPI PET-CT in diagnosing endometriosis. The results will be compared with surgical findings, pathology, and other imaging techniques if available (i.e., MRI, US).
Eligibility
Inclusion Criteria5
- Female participants aged 18-45 years
- Clinical suspicion of endometriosis based on symptoms
- Scheduled for diagnostic/therapeutic laparoscopic surgery
- Ability to understand and provide written informed consent
- Completed and signed Radiation Exposure Documentation Form
Exclusion Criteria4
- Pregnant women or women who are breastfeeding
- History of pelvic radiation therapy
- Known active malignancy
- Exposure to ionizing radiation for medical purposes within 12 months prior to enrollment
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Interventions
FAPI PET-CT imaging protocol: Single dose 68Ga/18F-FAPI (2 MBq/kg) Two imaging sessions: First: 10 and 30 minutes post-injection Second: 60 and 80 minutes post-injection Ultra-low dose CT for attenuation correction and anatomical localization
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06792318