Urethral PeRfusion Index-Guided Hemodynamic ManagemenT in Patients Having Major Abdominal Surgery: the UPRIGHT Randomized Feasibility Trial
Universitätsklinikum Hamburg-Eppendorf
116 participants
Jan 21, 2025
INTERVENTIONAL
Conditions
Summary
We will perform this single-center pilot trial to determine if the intraoperative urethral perfusion index is higher in patients assigned to maintaining postinduction baseline urethral perfusion index than in patients assigned to routine care (with blinded urethral perfusion index monitoring). As pre-planned substudies, we will also assess the agreement between a) urethral perfusion index-derived pulse rate and heart rate measured with an electrocardiogram and b) between the urethral perfusion index and the peripheral perfusion index.
Eligibility
Inclusion Criteria4
- at least 45 years old
- scheduled for elective major abdominal surgery (involving visceral organs with an expected duration of at least 120 minutes)
- indication for an arterial catheter
- indication for an urinary catheter
Exclusion Criteria4
- Pregnancy
- Planned surgery: nephrectomy, liver or kidney transplantation surgery
- Patients who previously had surgery on the urethra or bladder
- Patients without clinical indication for continuous blood pressure monitoring with an intraarterial catheter
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Interventions
The urethral perfusion index will be monitored using the IKORUS System (Vygon, Écouen, France)
Locations(2)
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NCT06799832